脉压指数与原发性高血压左心室功能的相关性研究  

Relationship between pulse pressure index and left ventricular function of essential hypertension

作　　者：梁维基 冼洪光 冯松青 

机构地区：[1]端州人民医院心血管内科,广东省肇庆市526040

出　　处：《中国心血管病研究》2009年第6期418-420,共3页Chinese Journal of Cardiovascular Research

摘　　要：目的探讨脉压指数（PPI）与原发性高血压患者左心室功能损害程度的关系。方法178例经外周肱动脉压力测定收缩压（sBP）、舒张压（DBP），以PPI〉0．40、PPI≤0．40分组，两组进行分析。比较两组左心形态、左心室收缩功能和舒张功能情况。结果PPI〉0．40组左心房内径明显增大[PPI〉0．40、PPI≤0．40的LAD分别为（35．02±3．15）mm、（28．05±2．01）mm，P〈0．05]；左心室内径无明显改变（P〉0．05）；室间隔、左心室后壁明显增厚，E／A值降低（P〈0．05），而左心室射血分数差异无统计学意义（P〉0．05）。结论原发性高血压患者左心室舒张功能异常出现早于左心室收缩功能异常，PPI〉0．40提示高血压患者早期合并有舒张功能异常。Objective To study the relationship between pulse index （PPI） and left ventricular funtion. Methods 178 patients, whose systolic blood pressure（SBP） and diastolic blood pressure （DBP） were measured through the peripheral humeral artery, were divided into two groups according to the PPI （PPI〉0.40 or PPI ≤ 0.40）. The geometrical figure of the left ventricle atrium and the systolic and diastolic function between two groups were compared. Results In the group （PPI〉0.40）, the average diameter of the atria was significantly larger（P〈 0.05 ）,and the ventricular septum and the posterior wall were significandy thicker （P〈0.05）, but the ejection fraction of left ventricular had no singificant difference between two groups. Conclusion The patients with essential hypertension often had left ventricular diastolic dysfunction early than ventricular systolic dysfunction, and PPI〉 0.40 may suggest the left ventricukar diastolic dysfunction in early stage of hypertension.

关 键 词：脉压指数 原发性高血压 左心室收缩功能不全 左心室舒张功能不全 

分 类 号：R544.1[医药卫生—心血管疾病]