刮痧前后大鼠胆红素、SOD、IL-1、IL-6、白细胞的变化  

Changes of bilirubin,SOD,IL-1,IL-6 and WBC count before and after Guasha treatment in rats

作　　者：王珂[1] 蒋燕[1] 张秋菊[1] 崔向清[1] 王婧[1] 

机构地区：[1]北京中医药大学基础医学院,北京100029

出　　处：《北京中医药大学学报》2009年第9期618-620,共3页Journal of Beijing University of Traditional Chinese Medicine

摘　　要：目的实验研究刮痧治疗疾病的作用机理。方法将Wistar大鼠40只,随机分为正常组、刮痧后0.5、6、12 h组,取动脉血分别进行血常规检测以及胆红素、超氧化物岐化酶(SOD)、白细胞介素-1(IL-1)、白细胞介素-6(IL-6)检测。结果刮痧后6 h组比正常组白细胞计数显著降低,总胆红素显著升高(P<0.05)。刮痧后12 h组SOD值比正常组显著降低(P<0.05)。结论刮痧作为一种诱导因素能够降低白细胞的炎性反应,这可能是其临床退热的作用机理之一;刮痧明显升高体内总胆红素水平,是其对疾病良好治疗作用的部分机理。Objective To study experimentally the mechanism of Guasha therapy in curing diseases. Methods All Wistar rats （ n = 40） were randomly divided into the normal group, group with 0.5 hour after Guasha （0.5 h group）, group with 6 hours after Guasha （6 h group） and group with 12 hours after Guasha （12 h group）. The arterial blood samples were collected and given blood routine examination. The levels of bilirubin, superoxide dismntase （SOD）, interlukin-1 （IL-1） and IL-6 were detected respectively. Results In the 6 h group the WBC count decreased significantly and the level of the total bilirubin increased significantly （P 〈 0.05 ） compared with those in the normal group. The level of SOD decreased significantly in the 12 h group compared with that in the normal group （ P 〈 0.05 ）. Conclusion The Guasha therapy can inhibit the inflammatory reaction of WBC and raise the level of the total bilirubin, which may be its one of the mechanisms for abating of fever and curing diseases.

关 键 词：刮痧 胆红素 超氧化物岐化酶 白细胞 大鼠 

分 类 号：R285.5[医药卫生—中药学]