856例不育男性染色体核型分析  

Analysis of Chromosome Karyotype in 856 Cases of Male Infertility

作　　者：吕福通[1] 谢丹尼[1] 陈美佳[1] 

机构地区：[1]广西壮族自治区人口和计划生育研究中心,南宁530021

出　　处：《中国计划生育学杂志》2009年第10期623-624,共2页Chinese Journal of Family Planning

摘　　要：目的:分析不育男性染色体核型,探讨染色体异常与不育症的关系。方法:对856例不育男性进行染色体检查,分析染色体核型,每例计数30个分裂相,分析10个核型,异常者加倍分析。结果:异常核型228例(包括染色体的多态性),异常检出率为26.64%。结论:染色体异常是导致男性不育的因素之一,在不育症的诊治过程中,应加强对染色体的检查。Objective： To explore the relationship between chromosome abnormality and male infertility by analyzing the karyo- types of infertile men. Methods ： The karyotypes of 856 of infertile men were analyzed. Thirty of mitotic figures were counted and 10 of karyotypes were examined for each man, and doubled for abnormal ones. Results： Of 856 cases of male infertility analyzed, 228 cases were karyotype abnormalities （ 26.64% ）. Conclusion ： The chromosomal abnormality is one of the factors that lead to male infertility. The chromosome examination should be strengthened in the diagnosis and treatment of infertility.

关 键 词：不育男性 染色体 异常核型 多态性 

分 类 号：R698.2[医药卫生—泌尿科学]