正交试验法优选冬凌草的提取工艺  

The choice of extracting process of the robdosia rubescens hemsl by the Method of Orthoonal test

作　　者：袁珂[1] 胡润淮[1] 翟剑波[1] 

机构地区：[1]河南中医学院,郑州450003

出　　处：《中国现代应用药学》1998年第5期14-15,共2页Chinese Journal of Modern Applied Pharmacy

基　　金：河南省科技攻关资助课题;第964025300号

摘　　要：目的:研究冷浸提取法中冬凌草的最佳提取条件.方法:采用正交试验法,以溶剂用量、提取时间和提取次数3个因素,每个因素选取3个水平进行实验.结果:因素A和因素B对冬凌草甲素的含量均有显著的影响,因素C则有一定的影响.结论:最佳工艺A_3B_3C_2,即用10倍量95%EtOH提取2次,每次6d.OBJECTIVE:To study the bset extracting conditions of robdosia rubescens hemsl in the cold - soaked way.METHODS:A orthogonal test method was used,the solvent dosage,extracting time and extracting times are the three factors in the experiment. And we choose three levels of each factor to do the experiment. RESULTS: The actor A and B has conspicuous effect on the concent of oridonin, the factor C has only certain effect. CONCLUSION: The best extracting process is A3B3C2,i e.extracting twice by using ten times of EtOH(95%) ,six days once.

关 键 词：正交试验法 冬凌草 冬凌草甲素 提取 工艺 

分 类 号：TQ461[化学工程—制药化工]