无水K_2CO_3催化合成苯偶姻乙酸酯  

Synthesis of Benzoin Acetate with Anhydrous Potassiuim Carbonate as Catalyst

作　　者：何强芳[1] 

机构地区：[1]广东教育学院化学系,广东广州510303

出　　处：《广东教育学院学报》2009年第5期93-96,共4页Journal of Guangdong Education Institute

摘　　要：以VB1为催化剂,苯甲醛为原料,通过安息香缩合反应得苯偶姻,再以无水K2CO3为催化剂,苯偶姻和乙酸酐通过酸酐醇解反应合成苯偶姻乙酸酯,研究了反应时间、碳酸钾、苯偶姻与乙酸酐的投料比对产品产率的影响.结果表明最佳的反应条件为∶n(碳酸钾)∶n(苯偶姻)∶n(乙酸酐)=1∶2∶10,在70℃水浴中回流反应60 min,获得的苯偶姻乙酸酯产率高达96.1%,并通过IR和1HNMR对苯偶姻乙酸酯的结构进行了表征.Benzoin was synthesized by benzoin condensation with phenyl aldehyde as raw material in the presence of VB1 as a catalyst. Benzoin acetate was synthesized by alcoholysis reaction with anhydrous potassium carbonate as alkaline catalyst. The preparation conditions were optimized by observing the effects of reaction time, n （ K2 CO3 ） ： n （benzoin） ： n （（CH3 CO）2 O） on the yield of benzoin acetate. The results showed that 98.1% of the yield of benzoin acetate was gained when the optimal process conditions were followed by n （K2CO3） ： n （benzoin） ： n （（CH3CO）20） = 1 ： 2 ： 10, reaction time of 60 min, and refluxing temperature of 70℃. The structure of synthesized benzoin acetate was characterized by IR spectrum and ^1HNMR.

关 键 词：苯偶姻 苯偶姻乙酸酯 乙酸酐 无水碳酸钾 

分 类 号：O626[理学—有机化学]