正常人群A、C群脑膜炎奈瑟氏菌免疫水平调查  

INVESTIGATION ON THE IMMUNE LEVEL OF THE MENITIS BACTERIUM TYPES A AND C AMONG THE NORMAL PEOPLE

作　　者：郑春早 王标[2] 邵荣标[1] 毕诚[3] 陈昌标[4] 蔡加平[5] 孙伯超 

机构地区：[1]江苏省盐城市疾病预防控制中心,盐城224002 [2]江苏省建湖县疾病预防控制中心 [3]江苏省疾病预防控制中心 [4]江苏省射阳县疾病预防控制中心 [5]江苏省东台市疾病预防控制中心

出　　处：《现代预防医学》2009年第20期3949-3950,3952,共3页Modern Preventive Medicine

摘　　要：[目的]了解盐城市正常人群A、C脑膜炎奈瑟氏菌(Nm)抗体水平状况,为制定流行性脑脊髓膜炎(流脑)防控措施提供依据。[方法]选择流脑发病水平不同的3个地区,按不同的年龄组采集一定数量的血清标本,采用酶联免疫吸附试验(ELISA)检测A、C群Nm抗体。[结果]在调查的正常人群中,A群Nm抗体阳性率为60.31%(541/897),几何平均滴度(GMT)为1︰7.79;C群Nm抗体阳性率为40.05%(342/854),GMT为1︰2.06。A、C群Nm抗体水平均处于较高的水平,相对而言,A群Nm抗体水平更高,这与长期以来广泛接种脑膜炎菌多糖疫苗有关。[结论]接种A、C群脑膜炎菌多糖疫苗效果是非常明显的,对预防和控制流脑具有重要的意义。[ Objective I To know the antibody of Nm type of A and C in healthy people, and to contro] the epidemic meningihs. [Methods] Three areas whose occurred rates of epidemic meningitis were different were selected, and the serum specimen in different age groups were gathered, and the antibody of Nm types A and C was detected with ELISA. [ Results] Among investigated people, the positive rate of antibody of Nm type A was 60.31% （541/897）, and the GMT was 1 ： 7.79; the positive rate of antibody of Nm type C was 40.05% （342/854）, GMT was 1 ： 2.06. The antibody t/ter of Nm type A and C were high. Relatively, the antibody titer of Nm type A was higher, which belonged to the inoculation of the polysaecharide vaccine in the long time. [Conclusion] Polysaccharide vaccine of Nm type A and C Inoculation was very good to prevent and control the Nm.

关 键 词：健康人群 脑膜炎奈瑟氏菌 抗体 监测 

分 类 号：R515.2[医药卫生—内科学]