聚乙烯醇基复合水凝胶的力学性能及摩擦系数评价  

The Appraisal of Mechanical Properties and Friction Coefficient of PVA Hydro-gel

作　　者：陈立奇[1] 张德坤[1] 张劲松[1] 

机构地区：[1]中国矿业大学材料科学与工程学院,徐州221116

出　　处：《生物医学工程学杂志》2009年第5期1021-1024,共4页Journal of Biomedical Engineering

基　　金：国家自然科学基金重点项目资助(50535050);教育部新世纪优秀人才支持计划项目资助(NCET-06-0479);江苏省自然科学基金创新人才项目资助(BK2005403)

摘　　要：为了提高聚乙烯醇(Polyvinyl alcohol,PVA)水凝胶的性能,我们提出了往水凝胶中添加胶原蛋白(Ge-latin)和羟基磷灰石(Hydroxyapatite,HA)的想法。采用反复冷冻-融化法制备了3种不同配比的PVA基复合水凝胶,利用微机控制电子万能试验机和UMT-Ⅱ型摩擦试验机等仪器,测试了相同PVA、HA含量,不同胶原蛋白含量的复合水凝胶的拉伸强度、弹性模量、蠕变量、应力松弛率以及摩擦系数曲线,分析了胶原蛋白和羟基磷灰石对PVA基复合水凝胶性能的影响。试验结果表明,不同含量的胶原蛋白对PVA/HA复合水凝胶的性能有较大影响;随着胶原蛋白含量的增加,PVA/HA复合水凝胶的性能并不严格符合正相关性,一些力学性能则是呈现先升高后降低的趋势;2wt-%胶原蛋白的PVA/HA复合水凝胶具有较好的性能:拉伸强度为5.5MPa,压缩弹性模量为1.48MPa,45min的蠕变率为31%,20min的应力松弛率为40.3%,启动摩擦系数为0.332。Gelatin and hydroxyapatite were introduced to polyvinyl alcohol （PVA） hydrogel with an attempt to enhance the performances of PVA hydrogel. Through a reiterative freezing-thawing methods, three kinds of PVA composite hydrogels were prepared. The mechanical performances of these composite hydrogels with the same PVA and HA content but varying gelatin content, such as tensile strength, elasticity modulus, creep curve, relaxation curve and friction coefficient were evaluated by using a computer-controlled universal electronic mechanical testing machine and a UMT-II frictional testing machine. The additional effects of hydroxylapatite and varying gelatin on the performances of composite PVA hydro-gels were analyzed. It was found that the gelatin content directly influenced the physical performances of PVA composite hydrogels, but no linear relationship was recorded. PVA composite hydrogel containing 2wt-% gelatin gave optimal results, i.e. tensile strength of 5.5MPa, compressive elastical modulus of 1.48MPa, creeping rate of 31 % in 45 minutes, stress relaxing rate of 40. 3M, and the starting friction coefficient of 0. 332.

关 键 词：PVA水凝胶 羟基磷灰石 胶原蛋白 力学性能 摩擦系数 

分 类 号：R318.08[医药卫生—生物医学工程]