外置式脑深部刺激器核心技术的突破  

Breakthrough of Technique for the Built-in DBS

作　　者：李刚[1] 白冰[1] 林凌[1] 

机构地区：[1]天津市生物医学检测技术与仪器重点实验室,天津大学,天津300072

出　　处：《中国医疗器械信息》2009年第9期24-27,共4页China Medical Device Information

基　　金：天津市应用基础及前沿技术研究计划(08JCZDJC19400)

摘　　要：针对脑深部刺激器的因电源耗尽需要定期更换、体积庞大、存在潜在危险的弊端，设计了一种体外供电的隔离脉冲发生电路。该电路根据电磁耦合原理，由经皮变压器、内置电路构成，与其它脉冲发生电路相比，在不需要附加通信信道的条件下，解决了至今为止刺激脉冲极性可控的难题，可实现刺激脉冲的极性、幅值、频率及脉宽多种参数的可控可调，而且电路极为简单。通过pspice仿真及实际电路的实验，实验结果与理论分析结果比较吻合，且幅值的变化范围为0～10V。因此设计的电路满足植入式刺激器对脉冲发生电路的需求，且该电路结构适用于大多数体外供电的植入式刺激器。Built-in power supply for Deeper Blain Stimulator （DBS） is not the optimal choice for implantable stimulators because of Limited lifetime, large volume and leakage risk to tissues. In view of these problems, an isolated pulse generator external powered is designed. Based on the electromagnetic coupling principle, the circuit consists of a transcutaneous transformer and the insided circuit. Compared with other pulse generator circuits, the circuit solves the difficult problem to control the polarity of stimulating pulses without additional communication channels realizing that the polarity, amplitude, frequency and pulse width of stimulating pulses are adjustable and controllable. By means of PSPICE emulation and real circuit testing, experimental result is consistent with expected result and the variable range of amplitude is between 0 and 10 voltages. So the designed circuit meets with the demand of pulse generator for implantable stimulators and this circuit is suitable for most of external powered implantable stimulators.

关 键 词：植入式刺激器 脉冲发生器 极性可控 多参数可调 触发器 

分 类 号：TP303.3[自动化与计算机技术—计算机系统结构]