茚虫威合成路线研究与比较  

Research and Comparison of the Synthetic Routes of Indoxacarb

作　　者：李翔[1] 马海军[1] 顾林玲[1] 俞小妹[1] 张红芬[1] 刘艳[1] 刘勇[1] 邢友华[1] 

机构地区：[1]江苏省农药研究所股份有限公司,南京210019

出　　处：《现代农药》2009年第5期23-26,共4页MODERN AGROCHEMICALS

摘　　要：通过实验对茚虫威的合成路线进行了比较,选择了以4-氯苯乙酸为原料,经过酰氯化、付-克烷基化等10步反应制备茚虫威的合成路线,所得茚虫威含量≥67%(S-异构体计),收率≥30%。The synthetic routes of indoxacarb were compared through a series of experiments.In the choosed route,4-chloro-phenylacetic acid was used as raw materials,and 10 steps reactions,such as acyl chlorination and Friedel-Crafts alkylation etc,were carried out.The yield of indoxacarb（calculated by S-isomer） was≥67%,the purity was≥30%.

关 键 词：茚虫威 合成路线 实验 评述 

分 类 号：TQ453.2[化学工程—农药化工]