120例川崎病临床分析  

Clinical analysis of 120 cases of Kawasaki disease

作　　者：卢玉容 袁杰[1] 何世娟[1] 

机构地区：[1]四川省宜宾市第二人民医院儿科,644000

出　　处：《重庆医学》2009年第19期2476-2477,2479,共3页Chongqing medicine

摘　　要：目的探讨川崎病(KD)的临床特征、实验室检查、冠脉损害的危险因素及治疗方法。方法对本院儿科2000年8月至2008年10月诊治的120例KD患儿资料进行回顾性分析和总结。结果120例KD中典型99例,不典型21例,男83例,女37例。平均发病年龄2岁7个月。合并冠脉损害者32例,其中冠脉扩张23例,冠脉瘤9例。对合并冠脉损害者随访6个月至3年,完全恢复正常者29例。结论不典型KD冠脉损害率高,KD发病10d内用丙种球蛋白效果好,2g/kg单次注射明显优于0.4g·kg-1.d-1连用5d的疗法,WBC升高,ALB降低,男性及发热时间长,是KD合并冠脉损害的危险因素。Objective To investigate the Kawasaki disease （KD） clinical features,laboratory examination, the risk factors for coronary artery lesion and treatment of kawasaki disease（KD）. Methods 120 cases of diagnosis and treatment of children with KD in pediatric of Second Hospital of Yibin city from August 2000 to October 2008 were reviewed and data was analysed and summarized. Results 120 cases of KD in 99 cases of typical,atypical in 21 cases,83 cases of male,37 cases of female. The average age of onset was 31 months. Combined 32 cases of coronary artery damage, there were23 cases of coronary artery expansion, 9 cases of coronary aneurysm. Combined damage to the coronary artery were followed up for 6 months to 3 years,29 cases fully recovered. Conclusion Atypical KD has a high rate of coronary artery lesion,and incidence of KD in 10 days with gammaglobulin was better than that with no gammaglobulin,2g/kg better than a single injection of 0.4g/kg （kg / d） once a 5d therapy. WBC increased,ALB lower,male and length of heat are timecombined KD of risk factors for coronary artery damage.

关 键 词：川崎病 不典型川崎病 冠脉损害 丙种球蛋白 

分 类 号：R725.4[医药卫生—儿科]