计帧法在冠状动脉血流缓慢中的应用及相关危险因素  

Clinical application in patients with coronary slow flow by Corrected TIMI Frame Count and risk factors for coronary slow flow

作　　者：邓昌明[1] 黄晶[1] 杨刚[1] 刘地川[1] 罗开良[1] 

机构地区：[1]重庆医科大学附属第二医院心血管内科,400010

出　　处：《重庆医学》2009年第19期2478-2479,共2页Chongqing medicine

基　　金：重庆市自然科学基金资助项目(CSTC2006BB5280)

摘　　要：目的探讨应用校正的心肌梗死溶栓治疗临床实验帧数(CTFC)方法测定冠状动脉血流缓慢患者血流速度的可行性,分析引起血流缓慢的相关危险因素。方法选取2000年10月至2008年9月心血管内科住院疑诊冠心病经冠状动脉造影证实的冠状动脉血流缓慢者78例;同时选取年龄、性别匹配的经冠状动脉造影证实的冠状动脉血流正常者78例为对照组,两组入选者均采用CTFC法测定冠状动脉血流速度。结果冠状动脉血流缓慢组CTFC帧数明显大于冠状动脉血流正常组,差异具有显著统计学意义。冠状动脉血流缓慢组低密度脂蛋白(LDL-Ch)明显升高,吸烟的比率增大。结论应用CTFC方法测定冠状动脉血流速度缓慢者是可行的,吸烟和LDL-Ch升高可能是引起冠状动脉血流缓慢的危险因素,戒烟和积极调脂治疗有助于改善冠状动脉血流速度,改善临床症状。Objective To investigate the possibility of clinical application in patients with coronary slow flow by Corrected TIMI Frame Count（CTFC）,and to investigate the clinical risk factors for the patients with coronary slow flow. Methods CTFC was measured in 78 patients with coronary slow flow confirmed by coronary angiography, and it was measured in age and sex matched 78 patiends with normal coronary flow. Results CTFC was significantly elevated in patients with coronary slow flow（P〈0.01）, the ratio of smoking was higher in patients with coronary slow flow than that in patients with nomal coronary flow, and LDL-Ch was elevated in patients with coronary slow flow. Conclusion The results suggest that CTFC is feasible in patients with coronary slow flow, smoking and elevated LDL-Ch may be the clinical risk factors for the patients with coronary slow flow.

关 键 词：冠状动脉疾病 血流速度 冠状动脉造影 

分 类 号：R541.4[医药卫生—心血管疾病]