活性炭负载单质碘催化合成季戊四醇单缩醛  

Synthesis of monoacetals of pentaerythritol catalyzed by iodinine supported on actived carbon

作　　者：袁先友[1] 张敏[1] 刘星明[1] 姜红宇[1] 

机构地区：[1]湖南科技学院化学与生物工程系,湖南永州425100

出　　处：《化学研究与应用》2009年第9期1265-1268,共4页Chemical Research and Application

基　　金：国家自然科学基金资助项目(50874044);湖南省重点学科建设项目(2006-180)资助;湖南省教育厅重点科研项目(08A023)资助

摘　　要：以活性炭负载单质碘为催化剂,合成了7种季戊四醇单缩醛。以正戊醛与季戊四醇的缩合为模型反应进行优化,其优化反应条件为:催化剂负载量为14.3%,催化剂用量为0.5g,季戊四醇14.7mmol,正戊醛17mmol,以25mL DMF为溶剂,反应4小时,单缩醛的产率达67.4%。产物经过元素分析、IR和1HNMR表征。Seven kinds of 2,2-bis（hydroxymethyl）-1,3-propanediol monoacetals were synthesized through condensation reaction of 2,2-bis（ hydroxymethyl）-1, 3-propanediol with aldehydes catalyzed by iodine supported on active carbon, and characterized by element analysis, IR, and ^1HNMR. The reaction conditions of n-valeraldehyde and 2, 2-bis （ hydroxymethyl）-1, 3-propanediol catalyzed by iodine supported on activeed carbon were investigated. Under the optimum reaction conditions（ catalyst loaded amount was 14.3% ,catalyst amount was 0.5g, 2,2-bis （hydroxymethyl） -1,3-propanediol was 14. 7mmol, n-valeraldehyde was 17mmol, DMF was 25mL,reaction time was 4h） ,the yield of monoacetal reached 67.4%.

关 键 词：活性炭负载单质碘 催化 季戊四醇 单缩醛 

分 类 号：O624.4[理学—有机化学]