山羊感染尼柯雅氏艾美尔球虫后的组织病理学研究  

STUDY ON HISTOPATHOLOGICAL CHANGES OF GOATS INFECTED WITH COCCIDIUM EIMERIA NINAKOHLYAKIMOVAE

作　　者：戴亚斌[1] 符敖齐[1] 陶建平[1] 陶红[1] 刘梅[1] 陈宗椿[1] 陈应江[1] 孙大明[1] 王军[1] 王伯高 谢龙 

机构地区：[1]江苏沿海地区农科所

出　　处：《江苏农学院学报》1998年第4期75-79,共5页Jiangsu Agricultural Research

基　　金：江苏省自然科学基金

摘　　要：对山羊感染尼柯雅氏艾美尔球虫后的病理学进行了研究。３５只无球虫感染山羊在２０日龄时，分别经口接种１×１０６～６×１０７个孢子化卵囊，在感染后１／４～３８ｄ内，定期扑杀，对其所致的病理变化进行了动态性观察。结果表明：尼柯雅艾美尔球虫主要侵害小肠后部、盲肠及结肠中前部的肠腺及粘膜上皮细胞，引起细胞坏死、上皮坏死脱落及小肠绒毛萎缩。肠系膜淋巴结肿大，被膜下、小梁周围的淋巴窦和淋巴管中有大裂殖体寄生。在感染１６ｄ后的山羊胆汁中发现了该球虫的卵囊、肝脏和胆囊有不同程度的病变，并在胆囊上皮细胞中发现了大、小配子体。尼柯雅氏艾美尔球虫具有较强的致病性。The pathology of infection with Eimeria ninakohlyakimovae in the goat was studied. Thirty five coccidia free goats were inoculated orally at 20 days of age with 1×10 6￣6×10 7 sporulated oocysts of E. ninakohlyakimovae , respectively, and killed at interval during 1/4￣38 days after inoculation. The histopathological changes of goats were observed. The results showed that E. ninakohlyakimovae mainly destroyed the cells in crypts and the epithelia in lower small intestine, caecam and upper and medium colon resulting in necrosis of the epithelia and lamina propria and atrophy of villi. Mesenteric lymph nodes were edematous and giant meronts were found in their cortical sinuses and lymphatic vessels. Oocysts of E. ninakohlyakimovae were found in bile of goats killed 16 days after inoculation. Liver and gallbladder showed various degrees of histopathological changes and macrogamonts and microgamonts were found in epithelial cells of gallbladders. E. ninakohlyakimovae showed a high pathogenicity for goats.

关 键 词：山羊 病理变化 感染 尼柯雅氏艾美尔 球虫 

分 类 号：S858.262.3[农业科学—临床兽医学]