血清淀粉酶及血清IgA检测在儿童腹型过敏性紫癜诊断中的价值  

Clinical Significance of Serum Amylase and Serum IgA in Children Henoch Purpura Patients

作　　者：皮光环[1] 田小兵[2] 马涛[3] 叶飘[3] 王媚[1] 黄越[1] 吴春[1] 陈玉蓉[1] 

机构地区：[1]川北医学院附院儿科,四川南充637000 [2]川北医学院预防医学教研室,四川南充637000 [3]四川省妇幼保健院急诊科,成都610041

出　　处：《中国循证医学杂志》2009年第9期1031-1032,共2页Chinese Journal of Evidence-based Medicine

摘　　要：目的探讨血清淀粉酶及血清IgA和总IgE在腹型过敏性紫癜(又称腹型紫癜)中的诊断价值。方法检测52例腹型过敏性紫癜患儿和69例无腹型过敏性紫癜患儿入院时的血清淀粉酶、血清IgA和总IgE水平,并与47例急性腹痛(胃、肠炎)组患儿进行比较。结果腹型组血清淀粉酶含量平均值为180.3±15.8IU,明显高于非腹型组和急性腹痛组(F=32.214,P=0.009);腹型组血清IgA增高病例占44.2%,与非腹型组无明显差异,但两组均高于急性腹痛组(χ2=13.73,P=0.001);腹型组总IgE增高病例占40.4%,三组差异无统计意义(χ2=1.80,P=0.41)。结论血清淀粉酶增高结合血清IgA增高可作为以腹痛起病的儿童过敏性紫癜诊断的参考指标,而血清总IgE意义不大。Objective To investigate the clinical significance of the level of serum amylase and serum IgA and total IgE in henoch-schonlein purpura patients with gastrointestinal involvement（also known as ＂Henoch purpura ＂）.Methods Levels of serum amylase and serum IgA and total IgE in henoch-schonlein purpura patients with or without abdominal pain or patients with acute abdominal pain were compared.Results The average level（180.3 ± 15.8 IU）of serum amylase of Henoch purpura patients was significantly higher than HSP patients without abdominal pain and acute abdominal pain patients （F=32.214, P=0.O09）; Ratio of cases of increased level of serum IgA in henoch purpura abdomen patients was 44.2%, and there was no significant difference with HSP patients without abdominal pain. But ratio of two groups was respectively higher than the acute abdominal pain patients group （χ^2=13.73, P=0.001）; Ratio of cases of increased level of serum IgE in Henoch purpura abdomen patients accounted for 40.4%, but there was no significant difference among the three group （χ^2=l.80, P=0.41）. Conclusion Levels of serum amylase increase and serum IgA increase conduce to diagnose HSP patients with the onset of abdominal pain, and serum total IgE has little significance.

关 键 词：腹型过敏性紫癜 血清淀粉酶 血清IGA 

分 类 号：R725.5[医药卫生—儿科]