全方向M型超声心动图对肥厚型心肌病患者左心室短轴心内外膜运动速度变化的研究  

A study of endocardial and epicardial motion velocity change on left ventricular short axes in patients with hypertrophic cardiomyopathy using omnidirectional M-mode echocardiography

作　　者：郭薇[1] 胡扬[2] 陈斌[1] 

机构地区：[1]福建省立医院心血管病研究所,福州350001 [2]福建医科大学省立临床学院

出　　处：《中华医学超声杂志（电子版）》2009年第5期26-29,共4页Chinese Journal of Medical Ultrasound(Electronic Edition)

基　　金：卫生部科研基金-福建省卫生教育联合攻关计划项目(WKJNo.2005-2-010)

摘　　要：目的评价全方向M型超声心动图定量肥厚型心肌病患者左心室短轴心内外膜运动速度变化的临床意义。方法将25例肥厚型心肌病(HCM)患者作为HCM组,30例健康体检者作为对照组。应用全方向M型超声心动图测量两组左心室短轴各节段的心内外膜运动速度及厚度。结果30例正常人的左心室短轴基底水平、乳头肌水平至心尖水平的心内外膜运动速度及速度差呈递减趋势。30例肥厚型心肌病患者与对照组比较左心室不同节段心内外膜运动速度及速度差值均有改变(P<0.01,P<0.05),且与相对应的室壁厚度有良好的相关性(r值范围在-0.60～-0.88)。结论心内外膜运动速度及速度差的变化能够反映肥厚型心肌病患者心肌受损的程度及心肌功能,全方向M型超声心动技术具有同时显示全方位任意角度的多个节段心肌运动的特点,具有重要的临床意义。Objective To evaluate the clinical practice of quantifying the change of endocardial and epicardial motion velocity （ EEMV ） using omnidirectional M-mode echocardiography （OME） in patients with hypertrophic cardiomyopathy （HCM）. Methods A total of 25 patients with HCM （16 males and 9 females, age 50.8±21.3 years） and 30 healthy volunteers（18 males and 12 females, age 29.0±10.9 years） were included in the HCM and control groups, respectively. A LEJ-2 mode OME was used to measure the EEMV and the thickness of every segment on left ventricular short axes. Results In the control group, EEMV and velocity gradient were found to be decreased progressively from base plane, papilla muscle plane to apical plane of left ventricular short axes. While the EEMV and velocity gradient of left ventricular segments in the HCM patients were significantly decreased compared to the control group （P〈0.01） . Further-more, the EEMV and velocity gradient were correlated significantly with corresponding wall thickness. Conclusion The change of EEMV and velocity gradient can reflect degree of myocardial injury and myocardial function in the patients with HCM. LEJ-2 mode OME with promising clinical applicability could monitor the myocardial synthetic motion of different segments at any angle simuhaneously.

关 键 词：超声心动描记术 肥厚型心肌病 心内外膜运动速度 

分 类 号：R542.2[医药卫生—心血管疾病]