妊娠期糖尿病发病相关因素分析  

CORRELATIVE FACTOR ANALYSIS OF GESTATIONAL DIABETES MELLITUS

作　　者：杜鹃[1] 辛刚[2] 刘培淑[3] 

机构地区：[1]济南市妇幼保健院,济南250000 [2]山东大学第二医院 [3]山东大学齐鲁医院

出　　处：《现代预防医学》2009年第19期3654-3656,共3页Modern Preventive Medicine

摘　　要：[目的]分析妊娠期糖尿病(Gestational Diabetes Mellitus,GDM)发病率及发病相关因素。[方法]收集单胎妊娠分娩产妇6 125例,其中GDM产妇129例,统计其可疑危险因素,运用Logistic分析GDM的危险因素。[结果]50 g糖筛查(50 g glucose challenge test,50 g GCT)异常发生率为5.50%(337/6125);GDM发生率为2.11%(129/6125)。对GDM的主要可疑危险因素,按作用大小依次为:孕前体重指数(BMI)、体重、家族史、年龄。对年龄进行分层分析显示:正常血糖组、GIGT组、GDM组3组间平均分娩年龄呈升高趋势,差异有统计学意义(F=33.80,P﹤0.01)。对体重指数进行分层分析显示:与低BMI相比,高BMI组发病危险增加,当BMI﹥24时其OR值为3.44(P﹤0.05)。[结论]GDM的主要危险因素依次是孕前体重指数、体重、家族史、年龄。[Objective] To analyze the incidence of gestational diabetes mellitus （GDM） and its influence on the pregnancy. [Methods] Analyzed the risk factors of 129 pregnant women with GDM among 6 125 singleton pregnant women using Logistic regression analysis method in Jinan Maternal and Infant Health Care Hospital in 2006. [ Results ] The abnormal rate of 50g glucose challenge test （50g GCT） was 5.50% （337/6 125）, and the incidence rate of GDM was 2.11% （129/6 125）. The major suspect risk factors of GDM were progestational body mass index （BMI） , body weight, fanuly history, and age. Stratified analysis on age showed the average delivery ages of normal glucose group, GIGT group and GDM group displayed a rising tendency. The result had a statistical significance （F=33.80, P 〈 0.01 ）. Stratified analysis on BMI showed the morbidity risk of high BMI group was higher than low BMI group, and its OR value was 3.44 when BMI 〉 24 （P 〈 0.05）. [Conclusionl The sequence of the major suspect risk factors of GDM was progestational body mass index, body weight, family history and age.

关 键 词：妊娠期糖尿病 回顾性分析 发病率 发病相关因素 

分 类 号：R587.1[医药卫生—内分泌]