取消苯甲醇肌注对预防臀肌挛缩症的初步评价  

PRELIMINARY CLINICAL ASSESSMENT ON THE PREVENTION OF GLUTEAL MUSCLE CONTRACTURE BY ABOLISHING BENZENEMETHANOL MUSCLE INJECTION

作　　者：唐学阳[1] 刘利君[1] 辛文琼[1] 刘榴[1] 彭明惺[1] 

机构地区：[1]四川大学华西医院小儿外科,成都610041

出　　处：《现代预防医学》2009年第19期3789-3791,共3页Modern Preventive Medicine

摘　　要：[目的]初步评估四川地区1983～2007年来针对注射性臀肌挛缩症(gluteal muscle contracture,GMC)病因的预防效果,探讨下一步的防治措施。[方法]描述性分析自1983～2007年我院共收治臀肌挛缩患者480例的临床流行病学特点,包括每年收治病例的数量、年龄、来源地区和苯甲醇/青霉素肌肉注射的变化情况。[结果]25年来每年收治病例逐年递增,1989年及以前出生者占80.21%(385/480),1990年后出生的病例仅占19.79%(95/480);有明确的苯甲醇/青霉素肌肉注射史者在前者占59.2%(228/385),后者仅40%(38/95);新发病例主要分布地区在1990年后有明显变化。[结论]苯甲醇/青霉素肌肉注射是GMC最重要的致病因素,通过禁止苯甲醇作为青霉素溶剂进行肌肉注射可有效防止GMC的发生。[Objective] To evaluate the results of preventing gluteal muscle contractare （GMC） from 1983 to 2007 in Sichuan Province and discuss the next prevention and treatment for the disease. [ Methods] 480 patients suffering from GMC during the 25 years from 1983 to 2007 were analyzed to know the clinical epidemiological characteristics, including amount of cases in each year and their ages, the regions where they came from and whether they had received the injections of benzenemethanol-penicillin into glutea muscles. [ Results] The patients increased year by year. 80.21% of them （385/480 eases） were born in 1989 and before, but only 19.79% of them （95/480） were born in 1990 and after. and the benzenemethanolpenicillin injection rates were 59.2% （228/385） and 40% （38/95）, respectively. The main regions where patients came from changed since 1990. [Conclusion] The most severe etiological factor is the rejection of benzcnemethanol-penicillin into gluteal muscles and abolishing injection of penicillin dissolved by benzenemethanol into gluteal muscles can help to prevent GMC.

关 键 词：臀肌挛缩症 肌肉注射 苯甲醇 青霉素 

分 类 号：R685[医药卫生—骨科学]