氦氖激光照射对大鼠皮肤烫伤愈合后期再创伤修复的影响  

Effect of He-Ne laser irradiation in healing process of skin scalded wound in rats

作　　者：刘筑闻[1] 王春燕[1] 马宗廉[1] 周康[1] 戚智[1] 

机构地区：[1]首都医科大学生物医学工程系

出　　处：《激光杂志》1998年第6期54-56,共3页Laser Journal

摘　　要：用波长为６３２８ｎｍ的低强度氦氖激光以三种不同剂量对４０只大鼠，４０个皮肤烫伤创面照射，观测到：一、创面的平均愈合时间均较未照射激光的创面缩短。二停止照射后即行切除全皮的新创面愈合时间则较未照射激光的新创面出现延长。三、以上两项效果均与照射剂量有关，愈合过程中各阶段的愈合速率也有不同。初步认为低强度氦氖激光（６３２８ｎｍ）照射对大鼠皮肤烫伤的愈合有促进作用；对停止照射后即受到之新的开放性创伤有延迟愈合的抑制作用趋势；以小剂量照射效果更为明显，且此效果主要显示在愈合后期。因此，在临床治疗中须注意被照射之创面痊愈前不可再受新的创伤。The 632.8nm wavelength low intensity He-Ne laser was used to irradiate on 40 rats which have skin scalded wound with three different laser dose.We observed that:(1).The wound healing process was accelerated by laser irradiation.(2).After laser irradiation for 14 days,the healed up skin was cut off,the healing process of the new wound was delayed than the group which also have new wound but without laser irradiation.(3).Both of above appearances were related with the laser dose.In each stage of healing process,the healing speeds were different.Our observation shows that the low intensity He-Ne laser (632.8nm)irradiation can accelerate the healing process of skin scalded wound in rats,but it can delay the healing process of new open cutting wound which was made after the laser irradiation,especially when using little dose laser.Thus,it must be noted that new wound should be avoided before the healing process completed.

关 键 词：低强度 皮肤烫伤 氦氖激光照射 

分 类 号：R454.2[医药卫生—治疗学] R758.1[医药卫生—临床医学]