头孢地尼治疗儿童急性化脓性中耳炎的临床观察  

Clinical observation of cefdinir treatment for suppurative otitis in children

作　　者：陈娜[1] 曹波[1] 

机构地区：[1]天津市儿童医院,天津300074

出　　处：《中国医院药学杂志》2009年第19期1648-1650,共3页Chinese Journal of Hospital Pharmacy

摘　　要：目的:评价头孢地尼颗粒剂治疗儿童急性化脓性中耳炎的疗效及安全性。方法:将门诊急性化脓性中耳炎患儿分为治疗组和对照组,每次分别口服头孢地尼颗粒剂5mg·kg-1,tid,头孢呋辛酯片15mg·kg-1,bid,疗程10d。结果:治疗组有效率94.6%;对照组有效率82.0%,2组有效率比较差异具有显著性(P<0.05),治疗组细菌清除率94.4%,对照组细菌清除率73.3%,2组细菌清除率比较差异具有显著性(P<0.05)。结论:头孢地尼颗粒剂治疗儿童急性化脓性中耳炎安全有效。OBJECTIVE To evaluate the granules of cefdinir in treating children with acute suppurative otitis media of the efficacy and safety. METHODS The patient with acute suppurative otitis media in children divided into treatment group and con trol group, each respectively cefdinir oral granules 5 mg·kg^ -1, rid, cefuroxime axetil tablets 15 mg·kg^ -1, bid , course of 11） d. RESULTS The treatment group was 94. 6%; control group, 82. 0% efficient, compared two groups of efficient statistical analysis of the difference was significant （P〈0. 05）, treatment group 94. 4% clearance rate of bacteria, the bacterial clearance rate of the control group 73.3%. Comparison of the bacterial clearance rates were significant differences （P-0.05）. CONCLUSlON Cefdinir granules in treating children with acute suppurative otitis media is safe and effective .

关 键 词：头孢地尼 化脓性中耳炎 儿童 

分 类 号：R969.4[医药卫生—药理学]