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作 者:张晓歌[1] 杨帆[2] 史宗道[3] 陈阳平[3] 张安翔[3]
机构地区:[1]四川大学口腔疾病研究国家重点实验室,成都610041 [2]四川大学华西医院,成都610041 [3]四川大学华西口腔医院,成都610041
出 处:《中国循证医学杂志》2009年第10期1124-1126,共3页Chinese Journal of Evidence-based Medicine
摘 要:目的总结有关口腔卫生护理的Cochrane系统评价证据。方法计算机检索Cochrane Library(2008年第3期)中有关口腔卫生护理的系统评价,并进行分析。结果共检索到4篇系统评价,内容涉及:手动与电动牙刷对维护口腔卫生的效果比较,应用牙间隙刷保持固定矫治患者口腔卫生的效果评价,初级口腔卫生护理的复诊间隔的选择,刮舌预防口臭的效果。结论目前缺乏高强度证据来支持牙间隙刷等口腔卫生护理的疗效。其他口腔护理方法的疗效如漱口水等尚需通过进一步的试验来评估。现有口腔卫生护理的系统评价纳入随机对照试验的方法学质量普遍较低,部分研究存在随机方法描述不清、无隐蔽分组、无样本量计算,以及无意向治疗分析等缺陷。建议推行临床试验透明化,实施临床试验注册制度,按照CONSORT声明规范报道随机对照试验,以便总结口腔卫生护理的临床证据,提高口腔卫生护理临床水平。Objective To assess the evidence of Cochrane systematic reviews relating to oral hygiene care. Methods Issue 3, 2008 of The Cochrane Library was searched for systematic reviews relating to oral hygiene care. Results Four systematic reviews with the forty-five randomized controlled trials (RCTs) were included. The methods of forty-five studies were of lower quality with high risk of various biases. Conclusion There is insufficient evidence to support oral hygiene care. The overall quality of RCTs about oral hygiene care is generally low. Analysis of the included trials shows some trials have no clear description of randomization methods, allocation concealment, sample size calculation, and intention-to-treat analysis. To improve the quality of reporting of RCTs, Clinical Trial Registration and Revised consolidated standards of reporting trial (CONSORT) statement should be introduced as guidelines into the trial design.
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