榕根生胶囊抗炎镇痛作用的实验研究  

Experimental Studies on Anti-inflammation,Analgesic Action for Ronggensheng Capsule

作　　者：伍曾利 展学孔 马小花[2] 刘全胜 马家骅[2] 

机构地区：[1]海南全星药物研究院,海南海口570216 [2]成都中医药大学,四川成都611173

出　　处：《中国实验方剂学杂志》2009年第10期92-94,共3页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:观察榕根生胶囊的镇痛及对大鼠佐剂性关节炎的抗炎消肿作用。方法:采用弗氏完全佐剂诱导大鼠佐剂性关节炎模型,观察足关节肿胀及炎症指数的改变:采用热板法与扭体法,观察榕根生胶囊对小鼠的镇痛作用。结果:榕根生胶囊能抑制大鼠继发性踝关节炎性肿胀,降低炎症指数;能延长热板法实验中小鼠舔后足的时间,能明显减少醋酸所致小鼠扭体的次数(P<0.05或P<0.01)。榕根生胶囊高剂量组抗炎消肿作用与美洛昔康组无明显差异。结论:榕根生胶囊具有较好的抗炎消肿和镇痛作用。Objective： Observing the influence of Ronggensheng Capsule on anti-inflammation, analgesic action and detumescence in the adjuvant-induced arthritis rat. Methods： Rat adjuvant arthritis model was established by Freund＇s complete adjuvant to observe the joint inflammation and swelling; and hot plate and writhing method to observe the Ronggensheng Capsule＇s analgesic effect in rat. Results： Ronggensheng Capsule could inhibit the rat secondary ankle swelling of arthritis, reduce inflammation index; extend the latent period of licking hind foot in the hot-plate test in mice and significantly reduce the acetic acid-induced writhing number in mice confirmed that high-dose group and meloxicam had no significant difference. good anti-inflammatory and analgesic effect on swelling. （P 〈 0.05 or P 〈 0.01）. Experi Conclusion： Ronggensheng Capsule ments has a

关 键 词：榕根生胶囊 佐剂性关节炎 抗炎 镇痛 关节炎指数 

分 类 号：R285.5[医药卫生—中药学]