紫外光解法研究醌类光敏剂对亚硝胺合成的阻断作用  

A study of quinones photosensitizer blocking synthesis of nitrosamines by ultraviolet photolysis

作　　者：黄娟[1] 鲍小丹[1] 赖强[1] 马建华[1] 

机构地区：[1]集美大学生物工程学院,厦门361021

出　　处：《辐射研究与辐射工艺学报》2009年第5期303-308,共6页Journal of Radiation Research and Radiation Processing

基　　金：福建省自然科学基金(2009J01032);厦门市集美区科技技划项目(350211Z20092C01);福建省教育厅基金(JA08136);集美大学中青年创新团队专向基金(2006A003)资助

摘　　要：利用紫外光解法研究了醌类光敏剂—2-磺酸钠蒽醌(AQS)和2-甲基-1,4-萘醌(MQ)对亚硝胺合成的阻断效果,并与相同条件下抗坏血酸(Vc)进行了对照。探讨了浓度、反应时间、紫外辐射波长对AQS、MQ阻断亚硝胺效果的影响。研究结果表明,反应时间1 h、反应浓度为0.96 mmol/L、紫外辐射波长365 nm时,AQS、MQ及Vc对亚硝胺的阻断率最高,阻断能力依次是:MQ>AQS>Vc。同时,用分光光度法测定了它们对亚硝酸盐的清除作用,发现相同条件下三者对亚硝酸钠的清除能力依次为:Vc>MQ>AQS。The effects of photosensitizer quinones -2 - sodium anthraquinone （AQS） and 2-methyl-1, 4-naph-thoquinone （MQ） on blocking synthesis of nitrosamine were studied by ultraviolet photolysis and compared with the same conditions of ascorbic acid （Vc）. The effects of determination conditions such as concentrations, reaction time and ultraviolet radiation wavelengths on blocking nitrosamines by AQS, MQ were investigated. The results show that when reaction time is lh, quinone concentration is 0.96 mmol/L, ultraviolet radiation wavelengths is 365 rim, their blocking rate could reach the highest value. The blocking capability followed by MQ〉 AQS〉 Vc. In the meantime, their cleaning action of nitrite has been determined by spectrophotometer, it has been found that under the same condition, their cleaning ability of nitrite followed by Vc 〉 MQ 〉 AQS.

关 键 词：磺酸钠蒽醌 萘醌 阻断亚硝胺合成 紫外光解法 

分 类 号：Q656.2[生物学—生物物理学] O625.462[理学—有机化学]