无明显黄斑水肿的糖尿病患者黄斑部厚度分析  

An analysis of macular thickness in diabetic patients whithout clinical macular edema

作　　者：孙冰[1] 王小中[1] 顾永昊[1] 柯根杰[1] 

机构地区：[1]安徽医科大学附属省立医院眼科,合肥230001

出　　处：《安徽医学》2009年第10期1180-1182,共3页Anhui Medical Journal

摘　　要：目的研究分析无明显黄斑水肿的糖尿病患者光学相干断层扫描(optical coherence tomography,OCT)所测黄斑部的厚度。方法糖尿病组52眼(30例),正常对照组40眼(20例)。分别行最佳矫正视力(best-corrected visual acuity,BCVA)、眼底等眼科常规检查,并散瞳行OCT黄斑厚度地图(macular thicknessmap)扫描。比较糖尿病患者和正常人的黄斑部厚度,并分析糖尿病患者黄斑部厚度与病程、BCVA之间的关系。结果糖尿病组病程(8.67±2.39)年,平均BCVA为4.65±0.47,黄斑部平均厚度为(267±46)μm,正常组平均BCVA为4.85±0.18,平均黄斑部厚度为(209±15)μm。无明显黄斑水肿的糖尿病患者黄斑部厚度增加,且与BCVA明显负相关,与病程正相关。结论OCT检测无明显黄斑水肿糖尿病患者的黄斑厚度变化,有利于诊断和监控早期糖尿病性黄斑水肿。Objective Investigate and analyze the of macular thickness in diabetic patients whithout clinical maeular edema with optical coherence tomography （OCT） measurements. Methods 52 eyes （30 cases） in diabetic group, 40 eyes （20 cases） in control group accepted examination of best -corrected visual acuity（BCVA）, fundus and macular thickness map scan by OCT. Macular thickness is analyzed and compared. Results In diabetic group, the cause of diabete is （8.67± 2.39） years, BCVA is 4.65±0.47, macular thickness is （267±46）μm. In control group, BCVA is 4.85±0.18, macular thickness is （209±15）μm. The macular thicknss of diabetic patients is greater than that of health persons, and significantly negatively correlate with BCVA, but postively correlated with the course. Conclusion OCT can detect macular thickness changes in diabetic patients whithout clinical macular edema. It is helpful for diagnosing and monitoring of early diabetic macular edema.

关 键 词：糖尿病性黄斑水肿 光学相干断层扫描 黄斑部厚度 病程 视力 

分 类 号：R587.1[医药卫生—内分泌] R774.5[医药卫生—内科学]