牛痘疫苗致炎兔皮提取物注射液对类风湿关节炎关节疼痛的疗效观察  

The effects of the Analgecine on joint pain of patients with rheumatoid arthritis

作　　者：潘云峰[1] 郭兴华[1] 肖楚吟[1] 吴玉琼[1] 

机构地区：[1]中山大学附属第三医院风湿免疫科,510630

出　　处：《中国现代医药杂志》2009年第9期32-33,共2页Modern Medicine Journal of China

摘　　要：目的探讨牛痘疫苗致炎兔皮提取物注射液(商品名:恩再适)对类风湿关节炎关节疼痛症状改善作用。方法恩再适注射液9ml加入0.9%生理盐水100ml静脉输注,1次/日,连续7天。结果治疗前(D0)患者VAS评分平均为8.2±1.2,治疗1天(D1)后VAS均值为5.6±1.3(P<0.01),治疗3天(D3)VAS均值为4.2±1.6(P<0.01),治疗7天(D7)降为2.6±1.2(P<0.01)。其中显效16例,有效10例,无效4例,显效率为53.33%,总有效率86.67%。所有患者药物输注过程中未出现明显不适,一周时复查血、尿、肝肾功能检查均未发现明显异常。结论恩再适对RA的关节疼痛具有显著缓解作用,可以作为类风湿关节炎的镇痛药物。Objective To find out the effects of the Analgecine on joint pain of patients with rheumatoid arthritis. Methods To test the VAS score changes and pain relief of patients before and after Analgecine treatment, at the same time to observe the safety. Results 16 cases were markedly effective, 10 were effective, 4 were Invalid, the significant effective rate was 53.33%, the total effective rate was 86.67%. Conclusion Analgecine can improve the symptom of joint pain in patients with RA, and can be used as a supplementary analgesic drugs in such patients who can not bear the NSAIDs or glucocorticoid.

关 键 词：恩再适 类风湿关节炎 疼痛 

分 类 号：R593.22[医药卫生—内科学] R684[医药卫生—临床医学]