基于导电聚合物吡咯膜的生物电化学传感研究  

Bioelectrochemical Sensors Based on Conducting Polymer—polypyrrole

作　　者：左国防[1] 

机构地区：[1]天水师范学院生命科学与化学学院,天水741000

出　　处：《高分子通报》2009年第9期62-68,共7页Polymer Bulletin

基　　金：甘肃省自然科学基金(3ZS061-A25-028)

摘　　要：导电聚合物可以与纳米尺寸的生物分子形成纳米复合物,在生物催化传感器的设计中,聚吡咯(Ppy)是应用最为广泛的一种导电聚合物,这种聚合物膜具有良好的导电性、选择性、稳定性、灵敏性以及生物相容性,很容易用于纳米尺寸生物分子的固定,并展示独特的催化和亲合特性。文章主要讨论了氧化还原酶在Ppy界面上的电子传递,提出了Ppy在免疫传感器、DNA传感器以及分子印迹技术领域中的最新应用及存在的问题,并对导电聚合物在未来分子技术中的发展进行了展望。Conducting polymers can be exploited as an excellent tool for the preparation of nanocomposites with nano-scaled biomolecules. Polypyrrole （Ppy） is one of the most extensively used conducting polymers in design of bioanalytical sensors based on it＇s favourable conductibility, selectivity, stability, sensitivity and biology affinity. In this review article significant attention is paid to immobilization of biologically active molecules within Ppy during electrochemical deposition of this polymer. Such unique properties of this polymer as facilitation of electron transfer from some redox enzymes are discussed. Recent advances in application of polypyrrole in immunosensors and DNA sensors are presented. Recent progress and problems in development of molecularly imprinted polypyrrole are considered too. This polymer will find propel place in future molecular technology.

关 键 词：导电聚合物 PPY 生物传感器 生物电化学 纳米生物技术 

分 类 号：TP212.2[自动化与计算机技术—检测技术与自动化装置]