血液病患者输血与庚型肝炎病毒感染的研究  

Study on hepatitis G virus infection in 63 posttransfusion patients with hematological diseases

作　　者：郑佳[1,2] 丁大成[1,2] 刘复强[1,2] 汪俊韬 吴昊 林秀玉[1,2] 

机构地区：[1]北京同仁医院血液科 [2]北京佑安医院

出　　处：《中华血液学杂志》1998年第12期649-651,共3页Chinese Journal of Hematology

摘　　要：目的：了解血液病患者输血后的庚型肝炎病毒（ＨＧＶ）感染情况。方法：对６３例血液病患者采用ＲＴＰＣＲ方法检测ＨＧＶＲＮＡ、丙型肝炎病毒（ＨＣＶ）ＲＮＡ，应用ＥＬＩＳＡ方法检测抗ＨＧＶ、ＨＢｓＡｇ。结果：ＨＧＶＲＮＡ阳性率为７．９％，抗ＨＧＶ阳性率６．３％；ＨＣＶＲＮＡ阳性率为４６．０％。ＨＧＶ感染通常伴有ＨＣＶ感染及丙氨酸转氨酶升高。ＨＧＶ感染与输血量有关，与血液病种类无关。结论：血液病输血可引起ＨＣＶ。Objective: To study the hepatitis G virus(HGV) infection in posttransfusion patients. Methods: HGV RNA and HCV RNA were detected by RT PCR, and anti HGV and HBsAg were assayed by ELISA in 63 posttransfusion patients with blood diseases. Results: The positive rates of HGV RNA, HCV RNA and anti HGV were 7.9%, 46.0% and 6.3%, respectively. HGV infection was usually accompanied by HCV infection and elevation of ALT. Conclusion: HGV as well as HCV may transmitted by blood transfusion.

关 键 词：血液病 输血 聚合酶链反应 庚型肝炎 

分 类 号：R512.630.4[医药卫生—内科学] R552[医药卫生—临床医学]