新型驱蚊药及其贴剂的实验室驱蚊效果观察  

Efficacy of Novel Home-Made Mosquito Repellents

作　　者：周珊宇[1] 张祝平[1] 麦晓丹[1] 李荣忠[1] 李乐[2] 何彦[1] 王春梅[3] 陈晓光[3] 

机构地区：[1]南方医科大学公共卫生与热带医学学院,预防医学2005级广州510515 [2]南方医科大学第一临床医学院 [3]南方医科大学公共卫生与热带医学学院病原生物学系,广州510515

出　　处：《热带医学杂志》2009年第9期1005-1007,1011,共4页Journal of Tropical Medicine

基　　金：南方医科大学创新教育基地基金(No.B1040522)

摘　　要：目的实验观察比较10种不同驱蚊配方的自制驱蚊贴对白纹伊蚊的驱避效果。方法利用DEET(N,N-diethyl-m-toluamide)、驱蚊植物精油、香精和无水乙醇配伍制成10种配方,加载在自行研制的驱蚊贴载药层上,在实验室进行对白纹伊蚊的驱避试验,并对驱蚊效果进行比较和分析。结果10种配方2h内的有效保护率组间比较差异有统计学意义(P<0.05)。其中9号配方效果最好,2h内平均有效保护率为(96.27±1.14)%,随之依次为10号(95.62±0.94)%、5号(95.30±0.64)%、6号(94.42±1.06)%、3号(93.69±1.82)%、2号(91.88±1.87)%、1号(89.47±2.34)%、8号(88.99±1.70)%、4号(85.52±1.98)%、7号(85.32±3.09)%。结论10种配方的自制驱蚊贴在驱蚊试验中有效保护率均达到80%以上,证明新剂型驱蚊贴为良好驱避剂剂型。Objective To compare the efficacy of ten formulations of home-made anti-mosquito patch to repel Aedes albopictus in the testing lab. Methods Ten different formulations of anti-mosquito patch were prepared by applying various doses of DEET, volatile oil, essence and absolute ethyl alcohol into the medicine-carrying layer of home-made patch. The effectiveness in repelling of Aedes albopictus was evaluated in the testing lab. Results All ten formulations of anti-mosquito patch were effective in repelling mosquito in the first 2 hours （P〈0.05）. Formulation No.9 is best in giving protection, with the effective protection rate in the first 2 hours of （96.27±1.14）%. The ranking of the ten formulations was in the order of No.9 （96.27±1.14）%, No.10 （95.62±0.94）%, No.5 （95.30±0.64）%, No.6 （94.42±1.06）%, No.3 （93.69±1.82）%, No.2 （91.88±1.87）%, No.1 （89.47±2.34）%, No.8 （88.99±1.7）%, No.4 （85.52±1.98）% and No.7 （85.32±3.09）%. Conclusion The effective protection rates of the ten anti-mosquito patch are all greater than 80% in the repelling experiments. The new formulations can be used as in the anti-mosquito patch.

关 键 词：白纹伊蚊 驱避剂 驱蚊贴 DEET 驱蚊植物精油 香精 

分 类 号：R384.1[医药卫生—医学寄生虫学]