邻苯二甲酸酯类化合物对男性生殖健康影响的研究进展  

Research Progress on Effects of Phthalate Esters on Male Reproduction Health

作　　者：陈晨[1] 孙增荣[1] 汤乃军[1] 

机构地区：[1]天津医科大学公共卫生学院劳动卫生与环境卫生教研室,天津300070

出　　处：《环境与健康杂志》2009年第10期934-937,共4页Journal of Environment and Health

基　　金：天津市科技支撑计划重点项目(09ZCGYSF01700)

摘　　要：随着现代化工业的高速发展,被广泛应用的邻苯二甲酸酯类化合物(phthalate esters,PAEs)对动物的生长发育和生殖系统造成了严重损害,同时,对人类也可能产生类似的影响。该文综述了国内外关于邻苯二甲酸酯类化合物对男性生殖健康的影响,并探讨了其对雄性激素影响的作用机制。With rapid development of modem industry, phthalate esters were used wildly in industry and it was found that phthalate esters can cause severe damages in animals growth, development and reproduction system. Even similar adverse effects might occur in human. On the basis of brief introduction for environment pollution situation about these compounds and the level of human exposure, this article introduced research advance made by scientists from various countries on phthalate esters affecting male reproduction health, and discussed the mechanism by which phthalate esters affect androgen.

关 键 词：环境内分泌干扰物 邻苯二甲酸酯类化合物 男性生殖系统 雄性激素 

分 类 号：R994.6[医药卫生—毒理学]