不同浓度七氟醚诱导麻醉对老年人血流动力学变化影响的研究  

The Effect of Sevoflurane-induced Anesthesia On the Haemodynamics in the Aged Population

作　　者：翟熠[1] 郭艳辉[2] 

机构地区：[1]中国医科大学附属第四医院麻醉科,沈阳110032 [2]中国医科大学附属第一医院麻醉科,沈阳110001

出　　处：《中国医科大学学报》2009年第8期630-631,634,共3页Journal of China Medical University

摘　　要：目的比较不同浓度七氟醚诱导麻醉对老年人血流动力学变化的影响,探讨适合老年人的吸入诱导方法。方法30例择期患者,随机分成3组(n=10):A组为七氟醚8%浓度组,B组为8%-6%-4%浓度递减组,C组为4.5%组,3组以不同浓度诱导,以脑电双频指数(BIS)值降至45以下为标准进行插管并记录插管时间,记录诱导期间血压心率以及心率变异性的变化。结果3组血压插管前与诱导前比较均降低,插管后与诱导前比较B组上升不明显,3组心率变异性比较无显著差异。结论七氟醚诱导平稳,无明显不良反应,8%-6%-4%七氟醚浓度递减组血流动力学更平稳,适合老年人诱导麻醉。Objective To compare the impact of sevoflurane-induced anesthesia on the changes of haemodynamics in the old patients.Methods Thirty ASA Ⅰ-Ⅲ patients were randomly assigned to three groups（n =10）according to the inhaling concentration o321 0f sevoflurane：A,8%;B,8%-6%-4%;C,4.5%.When BIS was reduced to 45,we performed the intubation and recorded the intubation time,MAP,HR,LF,HF and LF/HF.Results There was significant decrease in MAP of three groups between before intubation and induction （confusing）, while no significant increase of group B between after intubation and before induction. No significant difference in HR, HF, LF, and LF/HF was observed between before and after induction Conclusion The induction of sevoflurane was stable with safety and no side effect. Sevotlurane 8%-6%-4% is available for general anesthesia induction in the old patients.

关 键 词：双频指数 七氟醚 全麻诱导 

分 类 号：R614.2[医药卫生—麻醉学]