口腔矫治器治疗阻塞性睡眠呼吸暂停综合征的疗效分析  

The study on the correlation between the effect of dental appliances on OSAS and the morphology of upper airway and craniofacial structures

作　　者：刘月华[1,2] 曾祥龙[1,2] 傅民魁[1,2] 黄席珍 

机构地区：[1]北京医科大学口腔医学院 [2]北京协和医院

出　　处：《中华口腔医学杂志》1998年第6期365-368,共4页Chinese Journal of Stomatology

基　　金：国家自然科学基金

摘　　要：目的借助Ｘ线头影测量预测ＯＳＡＳ患者颅面形态与其口腔矫治器治疗效果的关系。方法２２例矫治器治疗的ＯＳＡＳ患者，将治疗前后多导睡眠监测所得的呼吸功能改变与治疗前Ｘ线头影测量值进行相关分析；同时根据患者疗效分组，比较不同疗效组颅面形态的差异。结果ＯＳＡＳ患者呼吸暂停指数的改善主要与颅面硬组织的形态有显著相关性；最低血氧饱和度的改善仅与下颌体长度及舌根部前后位置显著相关；而呼吸紊乱指数的改变与形态变量无显著相关性；不同疗效组间颅面结构存在明显差异，Ⅱ类高角特征越明显者，疗效越差。结论口腔矫治器治疗ＯＳＡＳ的疗效主要与颅面硬组织的形态有关，而与上气道的大小无显著相关性。Objective The purpose of this present study was to evaluate the effectiveness of dental appliances on OSAS by combining the use of overnight polysomnography and cephalometry. Methods 22 OSAS adult patients wore the dental appliances designed by authors. The association between the improvement of respiratory variables and the cephalometric variables were investigated on the basis of linear correlation analysis. We also classified the subjects by AI of post treatment to analyze the morphological disparity of upper airway and craniofacial structures among the groups. Results There was no significant correlation between the improvement of AI and the morphology of the upper airway and its surrounding soft structures, but there existed significant linear correlation between the improvement of AI and the morphology of the craniofacial skeletal structure. The improvement of the lowest SaO 2 was only correlated significantly with the body length of the mandible and the anteroposterior position of the base of tongue. However, the improvement of the RDI wasn't associated significantly with any morphological variables. In addition, there were morphological differences among the different groups. Conclusion The above findings suggested that the effectiveness of dental appliance on OSAS is mainly associated with craniofacial skeletal structures, but no correlation existed between the sagittal dimension of upper airway and the effectiveness.

关 键 词：呼吸暂停综合征 OSAS 口腔矫治器 治疗 

分 类 号：R563.905[医药卫生—呼吸系统] R783.5[医药卫生—内科学]