305例疑似NGU患者支原体培养及药敏分析  

Isolation and antibiotic susceptibility of mycoplasma in vitro Of 305 urine samples

作　　者：彭俊凤[1] 李耀军[2] 

机构地区：[1]陕西能源职业技术学院基础二部,陕西西安710613 [2]西安医学院第二附属医院,陕西西安710038

出　　处：《陕西能源职业技术学院学报》2009年第3期38-40,共3页

摘　　要：目的了解本地区支原体引起的尿道感染的状况以及对药物的敏感性，指导临床合理用药。方法采用支原体培养、药敏一体化试剂盒，对305例尿道支原体感染患者的10种抗生素的体外药敏试验结果进行统计分析。结果305例支原体培养标本中，阳性率48．2％（147／305）。其中解脲支原体（UU）阳性111例（36．4％），人型支原体（Mh）阳性6例（2．0％），UU合并Mh阳性30例（9．8％）；30～39岁年龄段发病率达57．6％；女性标本支原体感染率为58．8％（120／204），男性标本支原体感染率为26．7％（27／101），两者差异有统计学意义。其中敏感率超过85％的药物依次为：强力霉素、克拉霉素、美满霉素、交沙霉素。对大观霉素和林可霉素敏感性最差，其敏感率均为4．1％。结论支原体在本地区对强力霉素、克拉霉素、美满霉素、交沙霉素等抗生素敏感性较高，对大观霉素和林可霉素类药物耐药率高，应引起临床重视。Aim To know the status of urinary infection caused by mycoplasma in our district and medicinal sensitivity and to instruct rational administration of drug in clinic. Methods Myc - oplasma culture and drug susceptibility test were carried out using one complex mycoplasma kit. The drug susceptibility of mycoplasma to 10 antibiotics was determined in samples from 305 cases of urogenital tract infection. Results For the 305 patients, positive rates for Uu were 48.2% （147/305）. There arel 1 lpatients who had the ureaplasma urealytieum（UU） and the positive ratio is 36.4%. 6 patients who had the myeoplasma ho -minis（Mb） and the positive ratio is2.0%. The positive ratio of 30 patients who had UU and Mh is 9.8%. More than57% is the age from 30 to 39. The positive ratio of female patients infected mycoplasma is 58.8% （120/204） and the ratio of masculine is 26.7% （27/101） ,they have statisti- cal significance. The drugs of susceptive rate over 85% are deoxycycline, clarithromyein , minocycline and josamycin. Conclusion The patients with mycoplasma from this region are more susceptibilitive to those 4 antibiotics, have a high resistance rate to spectinomyeine and lincomycin, which should be paid high clinical attention.

关 键 词：泌尿生殖道 支原体 药敏试验 

分 类 号：R695.1[医药卫生—泌尿科学]