异丁酸苯氧乙酯微波合成研究  

Study on synthesis of phenoxyethyl isobutyrate under microwave irradiation

作　　者：邓斌[1,2] 章爱华[3] 徐安武[2] 

机构地区：[1]湘南学院化学与生命科学系,湖南郴州423000 [2]中国科技大学合肥微尺度物质科学国家实验室,安徽合肥230026 [3]吉首大学化学化工学院,湖南吉首416000

出　　处：《宝鸡文理学院学报（自然科学版）》2009年第3期30-33,共4页Journal of Baoji University of Arts and Sciences(Natural Science Edition)

基　　金：湖南省自然科学基金资助项目(07JJ3017);湖南省教育厅优秀青年科研基金项目(06B089)

摘　　要：目的利用微波辐射技术,以活性炭固载对甲苯磺酸为催化剂,环己烷为带水剂,异丁酸和苯氧乙醇为原料合成异丁酸苯氧乙酯。方法考察了微波功率、微波辐射时间、醇酸摩尔比、催化剂和带水剂用量对酯化率的影响。结果实验表明,较优的反应条件为:固定异丁酸0.2 mol,微波功率450 W,微波辐射时间12 min,n(苯氧乙醇)∶n(异丁酸)=3.0∶1.0,催化剂用量2.5 g,环己烷15 mL,酯化率可达97.4%。结论催化剂易于回收且可重复使用,具有价廉易得、催化效果好、操作简单、无环境污染等优点。Aim Phenoxyethyl isobutyrate was prepared by esterification of phenoxyethyl alcohol and isobutyric acid in the presence of p-toluenesulfonic acid supported on activated carbon as catalyst and cyclohexane as azeotropic agent under microwave irradiation. Methods The influence of microwave irradiation power, microwave irradiation time, molar ratio of phenoxyethyl alcohol to isobutyric acid, the dosages of the catalyst and azeotropic agent on the yield were investigated. Results The optimized reaction conditions were as following： when the dosage of isobutyric acid was 0.2 mol, microwave power 450 W, microwave irradiation 12.0 min, the molar ratio of phenoxyethyl alcohol to isobutyric acid was 3.0 to 1.0, the amount of p -toluenesulfonic acid supported on activated carbon was 2.5 g and the amount of cyclohexane was 15 mL, the yield of esterification reached to 97.4%. Conclusion The catalyst could be easily recovered and reused, and had characteristics of low cost, high catalytic efficiency, wide availability, easy operation and environmental friendliness.

关 键 词：微波辐射 活性炭固载对甲苯磺酸 催化酯化 异丁酸苯氧乙酯 

分 类 号：O621.3[理学—有机化学]