米非司酮终止早期妊娠的临床观察  

Clinical Study of Terminating Early Pregnancy with Mifepristone

作　　者：宋梅[1] 甄卓[1] 李灿[1] 

机构地区：[1]武警天津总队医院妇产科,300162

出　　处：《中国医药指南》2009年第20期33-34,共2页Guide of China Medicine

摘　　要：目的探讨应用米非司酮终止早孕的效果。方法根据停经天数、血清hCG和B超检查,将早孕期妇女190例,随机分为停经≤35d（A组）;停经36～42d（B组）;停经43～49d（C组）,给予米非司酮150mg分次口服,观察末次口服后24h内胎囊排出情况。结果B组分次口服米非司酮24h后完全流产率明显优于A组和C组,阴道出血和不良反应低于A组和C组。结论米非司酮终止≤42d早孕是安全、有效的方法。Objective To explore the efficacy of terminating early pregnancy with mifepristone. Method 190 early pregnancy were randomly divided into amenorrhea days≤35d （group A）, amenorrhea days 36--42d （group B） and amenorrhea days 43--49d （group C） according to amenorrhea days, serum human chorionic gonadotropin-beta subunit and B-ultrasonic examinations. Each group were given 150mg mifepristone orally, and the fetal sac discharge situation were observed for 24 hours. Results The abortion rate in group B was better than group A or group C after 24h with oral mifepristone, while vaginal bleeding and side effects is law than Group A or Group C. Conclusion Mifepristone is safe and effective for termination of early pregnancy （≤ 42d）.

关 键 词：早孕 药物流产 米非司酮司酮 

分 类 号：R984[医药卫生—药品]