人胃粘膜肥大细胞的分布与超微结构  

DISTRIBUTION AND ULTRASTRUCTURAL STUDIES ON MAST CELLS IN HUMAN GASTRIC MUCOSA

作　　者：王彤[1] 景雅[1] 杨琳[1] 乔从进[1] 

机构地区：[1]山西医科大学组织胚胎学教研室,太原030001

出　　处：《解剖学杂志》1998年第6期538-541,共4页Chinese Journal of Anatomy

摘　　要：光镜观察了25例人胃底部组织甲苯胺蓝染色切片的粘膜肥大细胞的分布.电镜观察了5例人胃底活检材料内粘膜肥大细胞的超微结构.结果:人胃粘膜肥大细胞主要分布在粘膜的浅层和中层,与壁细胞的分布有密切的位置关系;人胃粘膜肥大细胞超微结构可分为T型与TC型两种,与啮齿类动物消化道T型和TC型肥大细胞的分布有所不同.结论:人胃粘膜肥大细胞释放的组胺可能刺激邻近的壁细胞分泌胃酸.The distribution of mucosal mast cells in the sections stained with TB from 25 cases of hu-man stomach fundus tissue was studied by light microscopy. 5 cases of gastroscopy biopsy were used to study the ultrastructural characteristics of mucosal mast cells by electron microscopy. It was found that mast cells were predominatly distributed in the up-middle region of the gastric mucosa and showed a close relationship with the distribution of the parietal cells. The ultrastruc-tural characteristics indicated that mast cells in human gastric mucosa coould be divided into T and TC types, which were different from the distribution of T and TC type mast cells in the murine digestive tract. Our results suggested that the histamine released from the gastric mucosal mast cells might be conducive to the acid secretion from parietal cells.

关 键 词：胃粘膜 肥大细胞 分布 超微结构 

分 类 号：R322.44[医药卫生—人体解剖和组织胚胎学] R333.2[医药卫生—基础医学]