慢性阻塞性肺疾病、肺心病人群防治的研究基线资料分析  

Analysis of basic data of the study on prevention and treatment of COPD and chronic cor pulmonale

作　　者：程显声[1,2,3,4,5] 李景周 张珍祥 刘国华[1,2,3,4,5] 华毅 李清[1,2,3,4,5] 徐希胜 赵玉霞[1,2,3,4,5] 徐永健 张学功 李亚辉 马秀平[1,2,3,4,5] 

机构地区：[1]中国医学科学院中国协和医科大学 [2]北京市房山区第一医院呼吸科 [3]同济医科大学附属同济医院呼吸科 [4]中国医科大学第二临床学院 [5]中国医科大学呼吸疾病研究所

出　　处：《中华结核和呼吸杂志》1998年第12期749-752,共4页Chinese Journal of Tuberculosis and Respiratory Diseases

基　　金：国家"八五"攻关课题资助

摘　　要：目的为制定“慢性阻塞性肺疾病（ＣＯＰＤ）、肺心病人群防治策略提供依据。方法１９９２年春对北京市房山区、湖北省潜江地区及辽宁省沈阳市远郊区、县在册的１０２２３０名村民中≥１５岁人群进行入户调查，把有慢性气道炎症病史或吸烟指数≥３００者列为调查对象，肺功能一秒钟用力呼气容积／用力肺活量（ＦＥＶ１／ＦＶＣ）＜７０％者诊断为ＣＯＰＤ，Ｘ线胸片或心电图符合国家诊断标准者为肺心病。结果≥１５岁者６７２５１人中男３３１１９人，女３４１３２人。应调查人群７４００人，实查６５３６人（应答率为８８３％），占≥１５岁人口的９７％。共查出ＣＯＰＤ患者２０２０例，总患病率为３０％，其中以北京为最高达４５％。单纯吸烟、单纯慢性气道炎症及吸烟＋慢性气道炎症者ＣＯＰＤ患病率分别为２４６％、３４７％及４０９％。ＣＯＰＤ患者病因组成上，单纯吸烟者为４０７％，慢性气道炎症者为２５％，既吸烟又有慢性气道炎症者为３０９％，与吸烟有关者高达７１６％。共诊断慢性肺原性心脏病４５２例，占ＣＯＰＤ的２３１％，占≥１５岁人口的６７‰，占全人口的４４‰。结论本基线调查资料显示，在我国ＣＯＰＤ和肺心病的患病率都很高，是危害人民健康的重大?Objective The basic data were analysed to carry out the project of “the study on prevention and treatment of COPD and chronic cor pulmonale population” and to provide some scientific basis for making strategies of prevention and treatment of COPD and chronic cor pulmonale in communities. Method The basic survey of the study was carried out on 102230 rural people in the spring of 1992. At first the family inquiry into the chronic airway inflammation history and smoking index≥ 300 were made in population aged 15 years or more. Those with FEV 1/FVC<70% in lung function were considered as having COPD, and chronic cor pulmonale was diagnosed according to national criteria by chest radiography and electrocardiography. Result There were 67 251 people aged≥ 15 years in 102 230 population, among them 33 119 were male and 34 132 were female. Of the 7 400 subjects who should be investigated, 6 536 subjects were really investigated (88.3%), which accounted for 9.7% of≥15 year population. 2 020 people were diagnosed as having COPD,the prevalence of COPD being 3.0% in total population(≥15 years), and the highest was 4.5% in Beijing. The prevalences of COPD in smokers, subjects with chronic airway inflammation history and both of them were 24.6%, 34.7% and 40.9%, respectively. The sole smoking accounted for 40.7% and chronic airway inflammation history for 30.9% in the all COPD causes, respectively. 71.6% of COPD were related to smoking. 452 patients were diagnosed as having chronic cor pulmonale, which accounted for 23.1% of COPD, for 6.7‰ of≥ 15 year population, for 4.4‰ in total population. Conclusion The basic data demonstrate that the prevalence of COPD and chronic cor pulmonale are quite high. There are remarkable differences of the prevalences among different regions. The primary causes of COPD and chronic cor pulmonale are smoking and chronic airway inflammation. The strategy of prevention and treatment of them should be a comprehensive one, the key measure be smoking ces

关 键 词：阻塞性肺疾病 肺心病 流行病 防治 

分 类 号：R563.901[医药卫生—呼吸系统] R541.501[医药卫生—内科学]