磁场对克山病心肌的保护作用——磁场对缺氧性心肌损伤大鼠血红细胞SOD活性及血浆MDA含量变化的影响  

THE PROYECTIVE ROLE OF MAGNETIC FIELD IN THE MYOCARDIUM OF KESHAN DISEASE——THE EFFECT OF MAGNETIC FIELD ON THE AVTIVITIS OF BLOOD ERYTHROCYTE SOD AND ON THE CONTENT OF SERUM MDA IN THE RATS WITH ISCHEMIC MYOCARDIAL INJURY

作　　者：赵福弟[1] 刘军[1] 高中兴 罗速[1] 赵锐[1] 初秋[1] 刘广盛[2] 宋晓范[2] 杨唯[2] 

机构地区：[1]吉林医学院 [2]吉林省地方病第二防治研究所

出　　处：《中国地方病防治》1998年第6期328-329,共2页Chinese Journal of Control of Endemic Diseases

摘　　要：本实验将大鼠随机分为4组:空白对照组、磁作用对照组、缺氧性心肌损伤组、缺氧性心肌损伤磁场治疗组。分别采用四氮唑蓝法和硫代巴比妥酸法测定各组大鼠血红细胞SOD活性及血浆MDA含量。结果表明:血红细胞SOD活性,缺氧性心肌损伤磁场治疗组明显高于缺氧性心肌损伤组(P<0.01),磁作用对照组高于空白对照组(P<0.05)。血浆MDA含量,缺氧性心肌损伤磁场治疗组明显低于缺氧性心肌损伤组(P<0.01)。初步证实,磁砀对缺氧性心肌损伤大鼠和健康大鼠心肌具有一定的保护作用,此种作用对缺氧性心肌损伤大鼠更为明显。提示:磁场对克山病心肌具有一定的保护作用。In this experiment, the rats were randomly divided into 4 groups: blank control group, magnetic effect group(MK group), ischemic myocardial injury group(IMI group). The activitis of blood erythrocyte SOD in IMI + MT group increased ( P > 0.01). The activitie of blood erythyrocyted SOD in ME group were higher than those of blood erythyrocyte SOD in-blank control group (P < 0.05) . Compared with IMI group, the content of serum MDA decreased in MI + MT group ( P < 0.01). The results showed that magnetic field might play a protective role in the ischemic myocardium and normal my -ocarium of rats,especially in the ischemic myocardium. It suggesced that magnectic field may have some protective effects on the myocardium of Keshan disease.

关 键 词：克山病 磁场 缺氧性 心肌损伤 保护作用 

分 类 号：R542.305[医药卫生—心血管疾病]