芳酰肼的制备及表征  

Synthesis and characterization of arylacethydrazide

作　　者：夏庆春[1] 何其庄[1] 沈智慧[1] 许东芳[1] 

机构地区：[1]上海师范大学生命与环境科学学院,上海200234

出　　处：《上海师范大学学报（自然科学版）》2009年第5期506-510,共5页Journal of Shanghai Normal University(Natural Sciences)

基　　金：国家自然科学基金(20671063);上海市稀土功能材料重点实验室(07dz22303);上海师范大学重点学科(DZL711);上海市重点学科建设项目(S30406)

摘　　要：酰肼类化合物是一类具有较高反应活性的有机化合物,可以用作药物、高聚物、染料和照相材料等许多重要的前体和有机中间体,在有机合成中起承上启下的作用.以芳香化合物和氯乙酸乙酯为原料经亲核取代制备了相应的芳香酯,然后经肼解合成了9种芳酰肼类化合物,并通过IR,1H NMR和元素分析对其结构进行了表征.Arylhydrazide is a kind of important synthetic intermediate with high reactivity, it can be used as drugs, polymers, dyes, photographic materials and many other important organic precursors and intermediates. In this article, 9 arylacethydrazides were synthesized through alkanlytion of ethyl chloroacetate to aromatic compounds and the exchange reactions between esters and hydrazine. The as-received compounds were characterized by IR, ^1H NMR and elemental analysis.

关 键 词：酰肼 中间体 合成 

分 类 号：O626.32[理学—有机化学]