氨溴索雾化吸入对慢性阻塞性肺疾病患者的祛痰效果  

Eliminating Sputum Effects of the Patients with Chronic Obstructive Pulmonary Disease by Ambroxol via Inhalation

作　　者：许敏昭[1] 胡洁容[1] 李培珍[1] 

机构地区：[1]广西医科大学第七附属医院护理部,广西梧州543001

出　　处：《解放军护理杂志》2009年第20期8-9,共2页Nursing Journal of Chinese People's Liberation Army

摘　　要：目的探讨慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者雾化吸入氨溴索祛痰效果。方法将60例COPD患者按入院先后顺序分为治疗组与对照组,每组30例。在常规使用敏感抗生素、解痉平喘、化痰治疗基础上,治疗组用氨溴索30mg+生理盐水10ml雾化吸入,对照组采用传统糜蛋白酶4000U+生理盐水10ml+庆大霉素8万U进行雾化吸入。比较两组患者雾化吸入后祛痰效果、患者满意度及患者的住院天数。结果经治疗后,治疗组比对照组的患者咳嗽咳痰减少、痰量减少、痰黏稠度降低、肺部干湿啰音减少,患者满意度高,住院时间缩短。两组间差异均有统计学意义(P<0.01)。结论氨溴索雾化吸入能有效地祛除COPD患者痰液,缩短住院时间,提高患者满意度。Objective To investigate the eliminating sputum effects of the patients with chronic obstructive pulmonary disease （COPD） by ambroxol via inhalation. Methods Sixty COPD patients were equally divided into the treatment group and the control group according to the admission sequence. Each group was 30 patients. The treatment group was given additional Ambr- oxol 30 mg ＋ saline 10 ml via inhalation on the basis of sensitive antibiotics,antispasmodics,antiasthmatic. The control group was treated with traditional chymotrypsin 4000 U ＋ saline 10 ml ＋ gentamicin fog to 80,000 U via inhalation. The eliminating sputum effect, the patients＇ satisfaction level and their length of hospitalization between the two groups were compared. Results After the treatment, the symptoms of cough, sputum volume, sputum viscosity, expectoration, pulmonary rales in the patients of the treatment group were significantly improved compared with control group（P〈0. 01）. The satisfaction level was significantly higher. And the length of hospitalizaiton was significantly lower in the treatment group compared to the control group （P〈0.01）. Conclusion Inhalation of ambroxol can effectively eliminate sputum, shorten length of hospitalization and improve satisfaction level for COPD patients.

关 键 词：氨溴索 雾化吸入 祛痰 效果观察 

分 类 号：R563[医药卫生—呼吸系统]