荭草花化学成分的研究  

Chemical constituents of flowers from Polygonum orientale

作　　者：李勇军[1] 何迅[1] 刘志宝[1] 黄勇[1] 兰燕宇[1] 王爱民[1] 王永林[1] 

机构地区：[1]贵阳医学院药学院,贵州贵阳550004

出　　处：《中国中药杂志》2009年第20期2613-2615,共3页China Journal of Chinese Materia Medica

基　　金：国家自然科学基金项目(30860366);国家科技部科技支撑计划课题(2006BA106A01-03);贵州省科技厅重大专项(黔科合[2007]6010)

摘　　要：目的:研究荭草Polygonum orientale花活性部位的化学成分。方法:应用色谱技术分离纯化,根据化合物理化性质和波谱数据鉴定其结构。结果:分离并鉴定了9个化合物,分别为高朦胧木素(alphitonin,1),3,4-二羟基苯甲酸甲酯(meth-yl3,4-dihydroxybenzoate,2),罗布麻宁(apocynin,3),山柰素-3-O-β-D-葡萄糖苷(kaempferol-3-O-β-D-glucoside,4),1,3,5-三羟基苯(1,3,5-trihydroxybenzene,5),3,3′-二甲氧基鞣花酸-4-O-β-D-葡萄糖苷(3,3′-dimethoxyellagic-acid-4-O-β-D-glucoside,6),山柰素-3-O-α-L-鼠李糖苷(kaempferol-3-O-α-L-rhamnoside,7),槲皮素-3-O-α-L-鼠李糖苷(quercetin-3-O-α-L-rhamnoside,8),山柰素(kaempferol,9)。结论:化合物2,4,5为首次从该种植物中分离得到,化合物1,3为首次从该属植物中分离得到。Objective：To study the chemical constituents in the active portion from the flowers of Polygonum oriental. Method：Chromatographic techniques were employed for isolation and purification of the constituents and their structures were determined by spectral analysis and chemical evidence. Result：Nine compounds were obtained and identified as alphitonin （1）,methyl 3,4-dihydroxybenzoate （2）,apocynin （3）,kaempferol-3-O-β-D-glucoside （4）,1,3,5-trihydroxybenzene （5）,3,3＇-dimethoxyellagic-acid-4-O-β-D-glucoside （6）,kaempferol-3-O-α-L-rhamnoside （7）,quercetin-3-O-α-L-rhamnoside （8）,kaempferol （9）. Conclusion：Compounds 2,4,5 were isolated from P. oriental for the first time and compounds 1,3 were firstly obtained from the genus Polygonum.

关 键 词：荭草 化学成分 

分 类 号：R284.1[医药卫生—中药学] R977.2[医药卫生—中医学]