苍术的化学、分子生药学和药理学研究进展  

Advances in chemistry,molecular biology and pharmacological of Cangzhu

作　　者：付梅红[1] 朱东海[1] 方婧[1] 宋红月[1] 杨滨[1] 熊玉兰[1] 

机构地区：[1]中国中医科学院中药研究所,北京100700

出　　处：《中国中药杂志》2009年第20期2669-2672,共4页China Journal of Chinese Materia Medica

基　　金：科研院所社会公益研究专项(2005DIA1J172)

摘　　要：对近年来苍术所含化学成分研究进行阐述,苍术中主要化学成分研究主要集中在挥发油成分,其挥发油中含有有效成分β-桉叶醇(β-eudesmol)、茅术醇(hinesol),苍术中还含有38种苷类化合物,同时归纳总结了近年来分子生药学RAPD技术在苍术方面的研究进展,研究结果显示苍术的化学成分、遗传分化和地理分布有一定的相关性,认为以地域为界划分南北苍术有一定道理且由于常年适应环境的需要茅苍术已发生遗传上的分化;系统的总结了苍术提取物在燥湿健脾、心血管系统、泌尿生殖系统、神经系统等药理学研究内容,研究结果显示茅苍术提取物在消化系统、心血管系统、泌尿生殖系统等方面具有药理活性。We described chemical composition in Cangzhu in recent years,volatile oil is the important chemical composition,The β-eudesmol,hinesol are active ingredient in volatile oil and there are 38 kind of glycosides. At the same time,we overview the applying of RAPD technology in atractylodes lancea. The results is that there are correlation in chemical composition,genetic differentiation and geographical distribution,there is some truth in bounded by a territorial division of the north-south Cangzhu,and genetic differentiation has been happened in atractylodes lancea to adapting the environment. We described advances of pharmacological in dampness spleen,cardiovascular system,genitourinary system,nervous system,and the results show that there are pharmacological activity in digestive system,cardiovascular system,genitourinary system of atractylodes lancea.

关 键 词：苍术 化学成分 药理 分子生药学 

分 类 号：R284.1[医药卫生—中药学] R285[医药卫生—中医学]