正已烷职业中毒及其毒理学研究进展  

Review on Occupational Poisoning and Toxicology of N-hexane

作　　者：赵乾魁[1] 周元陵[1] 周志俊[2] 

机构地区：[1]复旦大学附属金山医院,上海200540 [2]复旦大学公共卫生学院,上海200032

出　　处：《职业卫生与应急救援》2009年第5期249-252,共4页Occupational Health and Emergency Rescue

基　　金：国家"十一五"科技支撑计划任务(2006BAI06B01);上海市公共卫生重点学科建设计划(08GWZX0303);带头人计划(08GWD20)支持

摘　　要：正己烷作为溶剂在工业中的广泛应用已导致职业性中毒的发生慢性正己烷中毒事故近年来呈上升趋势,引起了全社会的重视。该文介绍了正己烷职业中毒机理、检测、生物标志物及诊断治疗等近年来的进展。N-hexane. a widely used industrial solvent, has caused many occupational heahh problems. Nowadays. chronic n-hexane poisoning is showing an increasing trend and causes much concern. This article summarized the recent research on the toxicology of n-hexane and the toxicological mechanism, the metabolism and metabolites, hiomarker, the diagnosis and treatment of occupational poisoning were presented.

关 键 词：正己烷 职业中毒 毒理学 

分 类 号：R135.1[医药卫生—劳动卫生]