幽门螺杆菌的培养检测及药物敏感性测定结果分析  

Analysis of Cultivation and Antibiotics Sensitivity on Helicobacter Pylori

作　　者：黄新明[1] 张松涛[1] 汤海涛[1] 

机构地区：[1]六安市人民医院,安徽237005

出　　处：《安徽卫生职业技术学院学报》2009年第5期91-92,共2页Journal of Anhui Health Vocational & Technical College

基　　金：安徽省卫生厅科研计划项目(编号06B062)

摘　　要：目的:探讨幽门螺杆菌培养检测法的适宜条件及其对常用药物的敏感性,为临床用药提供参考。方法:用改良Skirrow培养基对胃粘膜切除物行微氧培养分离幽门螺杆菌;用K-B法进行7种常用药物的敏感性检测。结果:326份标本共分离出120株幽门螺杆菌,培养阳性率为36.8%;对左氧氟沙星、庆大霉素、克拉霉素、氨苄西林的敏感率分别为96.67%、95.00%、91.67%、87.50%,其他药物的抑菌活性较差,而甲硝唑的抑菌率最低,仅为51.67%。结论:左氧氟沙星、庆大霉素、克拉霉素、氨苄西林等抗生素可作为根除幽门螺杆菌的首选药物,但最好是联合用药。Objective： To explore the conditions suitable for culture and the sensitivity of Helicobacter Pylori （HP） on antibiotics which are in common used in clinics. Methods： HP were isolated from removal of gastric mucosa by Skirrow modified and the sensitivity of 7 antibiotics were detected by KB. Results： 120 strains of Hp were isolated from 326 patients with chronic gastritis, culture-positive rate was 36.8 percent, the sensitivities of Levofloxacin, gentamicin, clarithromycin, ampicillin were 96.67%, 95.00%, 91.67%, 87.50%, respectively. Other antibiotic had low inhibitive effect on HP, and metronidazole was the lowest rate of suppression bacteria, only 51.67 percent, however. Levofloxacin, gentamicin, clarithromycin, ampicillin may be as the first choice on eliminating HP, it is the best combination, however.

关 键 词：幽门螺杆菌 培养 抗生素 敏感性 

分 类 号：R37[医药卫生—病原生物学]