左旋卡尼汀对冠心病并糖尿病患者的临床疗效观察  

Clinical Investigation of L-Carnitine on the Patients with Coronary Heart Disease and Type-Ⅱ Diabetes

作　　者：遇波[1] 程向荣 石穆穆[3] 

机构地区：[1]哈尔滨医科大学第五附属医院高干病房,黑龙江大庆163000 [2]黑龙江省鸡西市矿业集团总医院,黑龙江鸡西158100 [3]哈尔滨医科大学大庆校区,黑龙江大庆163319

出　　处：《中外医疗》2009年第29期88-89,共2页China & Foreign Medical Treatment

摘　　要：目的观察左旋卡尼汀对冠心病并糖尿病患者临床疗效。方法60例冠心病并糖尿病患者随机分为常规治疗组(对照组,30例)和左旋卡尼汀组(治疗组,30例),对照组给予抗血小板、钙离子阻滞剂、β受体阻滞剂及硝酸脂类药物等常规治疗治疗,治疗组在此基础上加用国产左旋卡尼汀5g静脉滴注,1次/d,连续用药21d。观察治疗前及治疗后患者的心绞痛发生次数、硝酸甘油片用量及血糖血脂的变化。结果与治疗前相比,治疗组的心绞痛发生次数、硝酸甘油片用量明显改善,同时血糖明显下降。结论左旋卡尼汀可以辅助治疗冠心病并糖尿病患者,减轻心肌缺血及临床症状,同时可降低血糖。Objective To evaluate the effects of L-carnitine on the with coronary heart disease and type-Ⅱ diabetes.Methods Sixty patients with coronary heart disease and type-Ⅱ diabetes were divided into conventional therapy group（control group,30patients） and L-carnitine therapy group（therapy group,30 patients）.The control group patients were given basic treatment;the therapy group were given L-carnitine 5gPd for 21 days in addition to the basic treatment.Angina pectoris attack frequency,weekly nitroglycerin consumption and glucose＆lipid in heart failure patients was observed before and after L--carnitine treatment. Results After treatment, angina pectoris attack frequency,weekly nitroglycerin consumption of patients increased significantly in L-carnitine group, accompanied by decrease in blood glucose level. Conclusion L--carnitine can be used as adjuvant therapy to improve the patients with coronary heart disease and type--Ⅱ diabetes.

关 键 词：左卡尼汀 冠心病 糖尿病 

分 类 号：R977[医药卫生—药品]