腰椎退变黄韧带的生物力学测定  

Biomechanical evaluation of degenerative lumbar ligamentum flavum

作　　者：上官磊[1] 樊星[2] 仲霄鹏[1] 罗卓荆[1] 

机构地区：[1]第四军医大学西京医院骨科,西安市710032 [2]第四军医大学西京医院整形外科,西安市710032

出　　处：《中国脊柱脊髓杂志》2009年第10期749-752,共4页Chinese Journal of Spine and Spinal Cord

摘　　要：目的:测定人腰椎黄韧带的生物力学指标,为研究黄韧带退变的力学机制提供依据。方法:30例腰椎退变患者为退变组,同时期的15例年轻腰椎外伤患者为对照组,黄韧带标本均取自两组患者L4/5间黄韧带。标本清洗、修剪后测量初始长度和横截面积。将标本固定在力学试验机上的夹具后,调零处理,对标本施加拉伸载荷,直至标本断裂,计算机自动输出实验数据,根据直接获得的位移、载荷数据,通过计算得出应变、应力以及弹性模量的数值,并对两组数据进行统计学分析。结果:对照组所能承受的最大拉力载荷为65.98±6.58N,退变组为81.39±8.32N;对照组位移为3.74±0.37mm,退变组为3.08±0.29mm;对照组应力为32.99±5.48MPa,退变组为41.59±3.72MPa;对照组应变为0.209±0.09,退变组为0.183±0.02;对照组弹性模量为157.79±5.76MPa,退变组为229.32±21.95MPa。各指标两组相比均有统计学意义(P<0.05)。结论:腰椎退变黄韧带与正常黄韧带相比,应力增加,应变降低,弹性模量增加,说明退变黄韧带抗拉伸作用增强,但弹性却降低,这可能与腰椎退变导致黄韧带受力改变有关。Objective：To evaluate the biomechanical index of degenerative ligamentum flavum in order to elucidate the potential mechanism.Method：30 patients with degenerative lumbar spine regarded as degenerate group and 15 patients with lumbar fracture regarded as control group were collected.The ligamentum flavum at L4/5 level were dissected from each patients.The samples were trimmed and the initial length and cross-section area were measured.Shimadza Autograph instrument was used to assess the mechanics index under flexion-extension load.Experimental datas （including displacement,load） were recorded by PC automatically and processed into strain and modulus statistically.Result：The maximum pull stress in control group was 32.99± 5.48 MPa,and in degeneration group was 41.59±3.72MPa.The displacement was 3.74±0.37mm and 3.08± 0.29mm for control group and degeneration group respectively.The stree was 32.99±5.48MPa and 41.59±3.72 MPa for control group and degeneration group respectively,and the strain was 0.209±0.09 and 0.183±0.02 for control group and degeneration group respectively,while the modulus was 157.79±5.76MPa and 229.32± 21.95MPa for control group and degeneration group respectively,with each parameters between two groups showing significant difference（P〈0.05）.Condusion：The degenerated ligmentum flavum has the characteristics of increased stress,lowed strain and increased modulus compared with normal ligmentum flavum,whieh indicate the mechanical mechanism of ligamentum flavum degeneration.

关 键 词：腰椎 黄韧带 退变 生物力学 

分 类 号：R681.5[医药卫生—骨科学] R318.01[医药卫生—外科学]