血清LAM-IgG对结核病诊断价值的研究  

Study on serum LAM-IgG for the diagnosis of tuberculosis

作　　者：张淑英 裴景亮[2] 刘光福 李鹏 

机构地区：[1]山东省潍坊市第二人民医院,山东潍坊261041 [2]山东省潍坊医学院附属医院检验科,山东潍坊261031

出　　处：《中国当代医药》2009年第19期18-20,共3页China Modern Medicine

摘　　要：目的:探讨LAM-IgG在结核的诊断、鉴别诊断及疗效观察中的价值,为结核感染的诊断和治疗提供依据。方法:采用酶联免疫吸附试验(ELISA)检测血清中的LAM-IgG,采用SPSS13.0统计分析软件进行数据处理和统计学分析。结果:LAM-IgG在活动性肺结核、非活动性肺结核、肺外结核和对照组的阳性率分别为88.5%(23/26)、28.6%(6/21)、83.3%(15/18)、3.2%(1/31);病例组与对照组比较,差异有统计学意义(P<0.05),活动性肺结核组与肺外结核组比较,差异无统计学意义(P>0.05),但两组与非活动性肺结核组比较,差异有统计学意义(P<0.05)。LAM-IgG诊断活动性肺结核和肺外结核的敏感性为86.4%,特异性为83.3%,准确性为90.7%。结论:LAM-IgG可以用作活动性肺结核和肺外结核的诊断、鉴别诊断以及活动性肺结核的疗效监测。Objective ：To investigate the value of LAM-IgG in the diagnosis, differential diagnosis and prognosis judgment of tuberculosis so as to provide a basis for diagnosis and treatment of tuberculosis. Methods：The LAM-IgG in serum were detected with Enzyme-linked immunosorbent assay （ELISA）. SPSS13.0 statistical software was used for data statistics. Results： The positive rate of LAM-IgG in active pulmonary tuberculosis, non-active pulmonary tuberculosis, extra- pulmonary tuberculosis and the control group were 88.5%, 28.6%, 83.3%, 3.2%, respectively. The positive rate of LAM- IgG in the case group was higher than the control group （P〈0.05）. The positive rates of LAM-IgG in active pulmonary tuberculosis group and extra-pulmonary were higher than non-active tuberculosis （P〈0.05）. The sensitivity, specificity, accuracy of LAM-IgG in the diagnosis of active pulmonary tuberculosis and extra-pulmonary tuberculosis groups were 86.4%, 83.3%, 90.7%. Conclusion：LAM-IgG have a higher sensitivity, specificity, accuracy in the diagnosis of active pulmonary tuberculosis and extra-pulmonary tuberculosis. It can be used as an indicator of diagnosis, differential diagnosis and prognosis judgment of tuberculosis in the active pulmonary and extra-pulmonary tuberculosis.

关 键 词：阿拉伯甘露聚糖脂 活动性肺结核 非活动性肺结核 肺外结核 

分 类 号：R446.11[医药卫生—诊断学]