镇咳宁糖浆中盐酸麻黄碱的HPLC测定  

HPLC DETERMINATION OF EPHEDRINE HYDROCHLORIDEIN ZHENGKENING SYRUP

作　　者：吴韶铭 王宜祥 

机构地区：[1]金华市药品检验所

出　　处：《中国医药工业杂志》1998年第10期468-469,共2页Chinese Journal of Pharmaceuticals

摘　　要：以Ｎｏｖａ－ＰａｋＣ１８柱，甲醇－０．０１ｍｏｌ／Ｌ磷酸氢二钾溶液（４９６）为流动相，采用反相ＨＰＬＣ法测定镇咳宁糖浆中盐酸麻黄碱的含量。平均回收率９８．２％，ＲＳＤ为１．３％。A HPLC determination of ephedrine hydrochloride in ZhengKeNing syrup was described.A reversephase C18 column was used and the mobile phase was methanol0.01 mol/L dipotassium hydrogen phosphate(4∶96)(adjusted pH to 2.5 with H3PO4).The linear range was 4～16 μg(r=0.9992).The average recovery and RSD were 98.2% and 1.3%,respectively.

关 键 词：镇咳宁糖浆 盐酸麻黄碱 高效液相色谱 

分 类 号：R974.2[医药卫生—药品] R927.2[医药卫生—药学]