酮咯酸氨丁三醇联合舒芬太尼用于术后镇痛的研究  

Effect of intravenous Ketorolac Tromethamine and sufentanil on postoperative analgesia

作　　者：张葆[1] 费卫东[1] 恽伟方[1] 李立[1] 

机构地区：[1]南京医科大学附属常州第二人民医院麻醉科,213003

出　　处：《中国老年保健医学》2009年第5期9-10,共2页Chinese Journal of Geriatric Care

摘　　要：目的评价静脉联合应用酮咯酸氨丁三醇和舒芬太尼对术后静脉自控镇痛(PICA)效果的影响及对舒芬太尼副作用的预防作用。方法选择全麻术后行静脉自控镇痛患者100例,随机分为两组,舒芬太尼组(A组)50例,舒芬太尼复合酮咯酸氨丁三醇组(B组)50例。术后24h持续监测SpO2、ECG、NBP,并进行VAS评分,观测可能出现的不良反应。结果两组镇痛效果无显著差异(P>0.05),但B组患者恶心呕吐以及瘙痒等副反应明显低于A组。结论舒芬太尼复合酮咯酸氨丁三醇组与单纯舒芬太尼相比,能明显减弱舒芬太尼产生的恶心呕吐以及瘙痒等副反应,并且可以增强舒芬太尼镇痛效果。Objective To investigate the effect of intravenous Ketorolac Tromethamine on sufentanil postoperative analgesia and prevention of adverse reaction caused by sufentanil. Methods One hundred patients undergoing general anesthesia who were prepared for patient-controlled intravenous analgesia were randomly assigned to two groups. Group A was given only sufentanil,while group B was given sufentanil combined with Ketorolac Tromethamine. Results There is no difference in analgesia between two groups,but incidence of nausea,vomiting and pruritus in group B is lower than in group A. Conclusion Combination of Ketorolac Tromethamine and sufentanil is effective in reducing adverse reaction caused by sufentanil ,and enhance analgesic effect of sufentanil.

关 键 词：患者静脉自控镇痛(PICA) 酮咯酸氨丁三醇 

分 类 号：R614[医药卫生—麻醉学]