冠心病患者超敏C反应蛋白与白介素-11水平相关性分析  

Correlation study between the circulation level of high sensitivity C-reactive protein(hs-CRP) and IL-11 in patients with coronary heart disease

作　　者：段东杰 

机构地区：[1]河南省汝州市第一人民医院,467500

出　　处：《中国医学创新》2009年第30期8-10,共3页Medical Innovation of China

摘　　要：目的探讨冠心病患者超敏C反应蛋白(hs-CRP)与白介素-11(IL-11)的关系。方法将82例冠心病患者,根据冠状动脉造影结果分为4组:稳定型心绞痛(SA)组16例,不稳定型心绞痛(UA)组24例,急性心肌梗死(AMI)组22例,对照组20例。测定所有研究对象血浆hs-CRP、血清IL-11的水平。结果对照组、SA组、UA组及AMI组hs-CRP水平呈逐渐增高的趋势,而IL-11的水平呈逐渐降低的趋势,两者线性负相关。结论 IL-11水平的降低可能是冠状动脉粥样硬化患者斑块形成的原因之一。Objective To explore the relationship between the circulation level of high sensitivity C - reactive protein （ hs - CRP） and soluble IL - 11 in patients with heart disease. Methods A clinical research wase accomplished in 82 patients who were diagnosed as coronary heart disease initially. Research objects were divided into four groups： 20 patients in the control group with negative result in coronary angiography, 16 patients in stable angina（SA） group, 24 patients in unstable angina（UA） group and 22 patients in acute myocardial infarction（AMI） group, hs - CRP and IL - 11 were measured in all of the objects. Results The plasma hs - CRP level were gradually rising from control group to AMI group and IL - 11 were gradually steping down. The level of hs - CRP and IL - 11 showed linear negative correlation. Conclusion The lower level of IL - 11 may be the one of reasons in plaque formation.

关 键 词：冠心病 超敏C反应蛋白 白介素-11 

分 类 号：R541.4[医药卫生—心血管疾病] R979.5[医药卫生—内科学]