白头翁提取物体外抗结核杆菌作用的实验研究  

Experimental study of effects of Chinese bulbul extracts againsting Mycobacterium Tuberculosis in Vitro

作　　者：王淑英[1] 刘萌萌 吴银萍[1] 岳苏华[1] 

机构地区：[1]河南科技大学医学院药理教研室,洛阳471000 [2]洛阳疾病控制预防中心结研所,洛阳471003

出　　处：《江西中医学院学报》2009年第5期42-44,共3页Journal of Jiangxi College of Traditional Chinese Medicine

基　　金：河南省科技攻关项目(62530007)

摘　　要：目的:观察白头翁提取物体外对结核杆菌的作用。方法:采用新鲜的人型结核分枝杆菌标准菌株(H37RV)、多药耐药以及速生结核菌株,分别接种于含有不同浓度白头翁正丁醇提取物、空白对照和阳性对照的结核菌培养基,观察结核分枝杆菌的生长情况。结果:空白对照组菌落生长情况正常,白头翁提取物组(1∶10～1∶20)均对新鲜结核菌和速生菌生长有抑制作用,其中白头翁提取物1∶10对多药耐药菌株到培养终止期(40 d)仍无细菌生长。经恢复培养40 d均无结核菌生长。结论:一定浓度的白头翁提取物在体外有抗结核菌的作用,且有不可恢复的杀灭作用。Objective：To observe Chinese bulbul extract againsting Mycobacterium Tuberculosis in Vitro, Method： Mycobacterium Tuberculosis（ H37RV）, muhidrug-resistant Tuberculosis and burgeoning Tuberculosis were respectively incubated in culture media with various content of the Chinese bulbul extract, blank control and positive control of TB medium The resules of growth of M. Tuberculosis were observed. Resuh：M. Tuberculosis was repressed in the culture medium with persisting to the end of the culture（40 d）. The grain on the medium surface of 1：10 - 1：20 of Chinese bulbul extract can not be developed into bacterium. Conclusion：M. Tuberculosis could be killed in certain concentration of Chinese bulbul extract in vitro, it is unrecoverable exterminate action.

关 键 词：白头翁提取物 结核分枝杆菌 体外试验 

分 类 号：R285.5[医药卫生—中药学]