氨酚羟考酮片用于骨科严重背痛的临床评价  

Efficacy of oxycodone-acetaminophen tablet in treating severe back pain in orthopedics

作　　者：李曙明[1] 彭文学 杜恒[1] 尹战海[1] 杨益民[1] 

机构地区：[1]西安交通大学医学院附属第一医院骨科,西安710061 [2]陕西省泾阳县医院,泾阳713700

出　　处：《中国新药杂志》2009年第20期1972-1974,共3页Chinese Journal of New Drugs

摘　　要：目的:评价氨酚羟考酮片(泰勒宁)对骨科严重背痛的临床镇痛效果。方法:采用对照试验,68例骨科严重背痛患者根据病情分为骨质疏松组(s组,n=33)与脊柱肿瘤组(z组,n=35),使用泰勒宁1～2粒,口服,tid,连续7d。采用视觉模拟评分法观察服药后疼痛程度变化及缓解程度。结果:两组患者均取得良好的镇痛效果,用药7d后中度以上疼痛缓解率和完全缓解率,z组分别为94.2%和57.1%,s组分别为100%和66.7%。结论:氨酚羟考酮片对骨科严重背痛有良好的临床镇痛效果。Objective： To evaluate therapeutic efficacy of oxycodone-acetaminophen tablet in treating severe back pain in orthopedics. Methods ： Patients with severe back pain （ n = 68 ） , including osteoporosis （ n = 33 ） and spinal tumor （ n = 35 ） , were treated with oral oxycodone-acetaminophen, 1 - 2 tablets, rid. for 7 days. Visual analogue scales were adopted to observe changes in degrees of pain severity and pain-relief. Results： Satisfactory effects of pain relief were observed in both groups. Moderate and complete pain reliefs were 94.2% and 57. 1% in spinal tumor group,and 100% and 66.7% in osteoporosis group 7 days after treatment with oxycodone-acetaminophen tablets. Conclusion： Oxycodone-acetaminophen tablet has satisfactory effect of pain relief in treating severe back pain in orthopedics.

关 键 词：背痛 氨酚羟考酮片 脊柱肿瘤 骨质疏松 

分 类 号：R971.1[医药卫生—药品]